A0A6S6M570 · A0A6S6M570_9BACT
- ProteinGamma-glutamyl phosphate reductase
- GeneproA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids418 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
Catalytic activity
- L-glutamate 5-semialdehyde + NADP+ + phosphate = H+ + L-glutamyl 5-phosphate + NADPH
Pathway
Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | glutamate-5-semialdehyde dehydrogenase activity | |
Molecular Function | NADP binding | |
Biological Process | L-proline biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGamma-glutamyl phosphate reductase
- EC number
- Short namesGPR
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfuromonadia > Geobacterales > Geobacteraceae > Citrifermentans
Accessions
- Primary accessionA0A6S6M570
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-293 | Aldehyde dehydrogenase | ||||
Sequence: AEQIRSIAAEARQASFAMAKLSSAAKDQLLLDMALALINDAPHIIEENKKDLEAGQQRGLSAAMLDRLMLNEQRVKGMADAIREVAQLPDPVGEVTGMWKRPNDLMVGKMRIPLGVIGIIYESRPNVTSDAAALCLKSGNAVVLRGGSEAIHSNLAIATILKAQLAKHGIPAAALSLIPFVEREGVTEMLKQEEYIDVIIPRGGESLIRFVVENSKIPVIKHYKGVCHIFVDATADFEMAREIIVNAKTQRPGVCNALETLLIHKDIAETFVPFIYEALSTLKVELRGDK |
Sequence similarities
Belongs to the gamma-glutamyl phosphate reductase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length418
- Mass (Da)45,512
- Last updated2020-12-02 v1
- ChecksumB64F48A7DD76AA79
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP023213 EMBL· GenBank· DDBJ | BCG48918.1 EMBL· GenBank· DDBJ | Genomic DNA |