A0A6S6M337 · A0A6S6M337_9BACT

Function

function

May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site56substrate
Binding site131substrate
Binding site191substrate
Binding site192-194NAD+ (UniProtKB | ChEBI)
Binding site221substrate
Binding site225substrate
Binding site226NAD+ (UniProtKB | ChEBI)
Binding site255-260NAD+ (UniProtKB | ChEBI)
Binding site257-262NAD+ (UniProtKB | ChEBI)
Binding site278NAD+ (UniProtKB | ChEBI)
Binding site313NAD+ (UniProtKB | ChEBI)
Binding site334-336NAD+ (UniProtKB | ChEBI)
Binding site379NAD+ (UniProtKB | ChEBI)
Binding site386NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionadenosylhomocysteinase activity
Biological ProcessL-homocysteine biosynthetic process
Biological Processone-carbon metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylhomocysteinase
  • EC number
  • Alternative names
    • S-adenosyl-L-homocysteine hydrolase
      (AdoHcyase
      )

Gene names

    • Name
      ahcY
    • ORF names
      GEOBRER4_n2896

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • R4
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfuromonadia > Geobacterales > Geobacteraceae > Citrifermentans

Accessions

  • Primary accession
    A0A6S6M337

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain226-385S-adenosyl-L-homocysteine hydrolase NAD binding

Sequence similarities

Belongs to the adenosylhomocysteinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    465
  • Mass (Da)
    51,292
  • Last updated
    2020-12-02 v1
  • Checksum
    81D16F5A47C1C6EA
MKENDYKVKDMSLAAWGRKEMIIAETEMPGLMAIREEYAASQPLKGARIAGSLHMTIQTAMLIETLTALGAEVRWASCNIFSTQDHAAAAIAAAGVPVFAHKGETLAEYWDYTHKIFEWHDGGAPNMILDDGGDATLLLHLGSDAEKNPSVIANPTCEEEQFLFAAIKKRLETEPGWYSKTAACIKGVTEETTTGVHRLYQMHEKGKLKFPAINVNDSVTKSKFDNIYGCRESLMDGIKRATDVMVAGKVAVICGYGDVGKGCAQAMRGLQAQVWVTEVDPICALQAAMEGYKVVTMEWAADKADIFVTTTGNIDVITHDHMKAMKHNAIVCNIGHFDNEIEVAKLKQYQWENIKPQVDHVIFPDGKRIILLAEGRLVNLGCATGHPSYVMSSSFANQTLAQMEIFCNPGKYPVGVYTLPKELDEKVARLQLKTLGAMLTELTDAQADYIGVKKEGPYKSEHYRY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP023213
EMBL· GenBank· DDBJ
BCG48030.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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