A0A6S6M053 · A0A6S6M053_9BACT

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site71Transition state stabilizer
Active site75Proton acceptor
Binding site238Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      GEOBRER4_03160

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • R4
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfuromonadia > Geobacterales > Geobacteraceae > Citrifermentans

Accessions

  • Primary accession
    A0A6S6M053

Proteomes

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link197↔223Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-74)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain108-397Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    711
  • Mass (Da)
    78,508
  • Last updated
    2020-12-02 v1
  • Checksum
    5325DC7D37F2F8FE
MNRDWWPNQLNLKILHQHSPLSNPMGGNFNYSEEFETLDLAAVRQDIFELMTTSQEWWPADYGHYGPLFIRMAWHSAGTYRTGDGRGGARSGSQRFAPLNSWPDNANLDKARMLLWPIKQKYGKKISWADLLIFAGNCALESMGFKTFGFGGGREDIWEPGEDIYWGAEDTWLGDTRYSGERLLENPLAAVQMGLIYVNPEGPNGNPDPLAAAKDIRETFARMAMNDEETVALIAGGHTFGKCHGAGAATHVGPEPEGASIIEQGLGWKCSFGTGKGEYTITSGLEGAWTTNPVKWDNGFFDVLFRYDWALTKSPAGAHQWTPTDPAAKGTVPDAHNPTKRHAPMMLTTDLALKLDPIYGPISKRFHEQPDVFADAFARAWFKLTHRDMGPRACYLGPQVPAEDLIWQDPLPARNHELIDDKDIAELKGKIITSGLSIPQLVSTAWASASTFRSSDRRGGANGARIRLAPQKDWEVNQPAQLKLVLETLEGIQKQFNSAQSGGKRVSIADLIVLGGCAAIELAARNAGHEVLVPFTPGRTDAKQEQTDVVAFAPLEPTADGFRNYLKARYSVSAEELLVDRAQLLTLSAPEMTVLIGGMRVLDANANQSRHGVFTKQPGTLTNDFFVNLLDMSTTWSATSEAEDVFEGRDRVTGEMKWTGTRVDLIFGSNSLLRAQAEVYGCKDSQEKFLLDFIAAWCKVMNLDRFDIAKS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP023213
EMBL· GenBank· DDBJ
BCG45566.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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