A0A6S6LX23 · A0A6S6LX23_9BACT

  • Protein
    Biosynthetic arginine decarboxylase
  • Gene
    speA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site282-292substrate
Active site502Proton donor

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Biological Processarginine catabolic process
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • ORF names
      GEOBRER4_n1332

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • R4
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfuromonadia > Geobacterales > Geobacteraceae > Citrifermentans

Accessions

  • Primary accession
    A0A6S6LX23

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue100N6-(pyridoxal phosphate)lysine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain86-342Orn/DAP/Arg decarboxylase 2 N-terminal
Domain371-449Arginine decarboxylase helical bundle
Domain584-633Arginine decarboxylase C-terminal helical

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    635
  • Mass (Da)
    71,685
  • Last updated
    2020-12-02 v1
  • Checksum
    A58AC59F83EFC1EA
MAKWTINDSSKIYNIDNWGAELFSINKKGNVCVHPSPNSKYSIDLKVLVDDLIKRKIKPPILLRFMNILEGRIASISRVFKNAISDNNYPAKYQTFYPIKVNQQRQVVEAIANFGKKYNIGLEVGSKPELVAAISMSTGNNLPILCNGYKDTEFIETVLFATRVGYDITIVVEKLFELEKIVEVSKRTGIVPKLGIRVKLSSKGIGKWSTSGGDDAKFGLRISELIAAIEMLKQNDMLDCVKLLHFHVGSQITKIDKIKNALIEGTRIYAEMRKLGVNLEFLDIGGGLGVDYDGSKSSYFSSVNYSLEEYANDVIYQVKNICDDAGVPCPNIISESGRATVAHYSVLVTDVLNNNPQTLMPDFESILTEPEKLSPTVKKLVDIYKSIDKHSLREDYHDTIQLIQESVSLFNLGYLNMAERANAEWICTKIIRKINSIVEKMKPIPDELQNFQLSLRQTYFANFSLFQSIPDSWAIDQLFPIVPIQRLDEKPDVSASIADITCDSDGEITSFVGENGRTKALPLHKIKVDEQYYIGFFLIGAYQEILGDMHNLFGDTNAVHITFNKKTNYKIDTVITGDATWESLKYVQYDSQEILKRVRNNLEKDVSLQKVSIEESSHFLELLDKTLQSYTYLGE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP023213
EMBL· GenBank· DDBJ
BCG46532.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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