A0A6S6FZK0 · A0A6S6FZK0_9SPHN

  • Protein
    NADH-quinone oxidoreductase subunit B
  • Gene
    nuoB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Features

Showing features for binding site.

118120406080100120140160180
TypeIDPosition(s)Description
Binding site60[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site61[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site125[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site155[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit B
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit B
    • NDH-1 subunit B

Gene names

    • Name
      nuoB
    • ORF names
      HMP06_1268

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • HMP6
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingomonas

Accessions

  • Primary accession
    A0A6S6FZK0

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain60-169NADH:ubiquinone oxidoreductase-like 20kDa subunit

Sequence similarities

Belongs to the complex I 20 kDa subunit family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    181
  • Mass (Da)
    20,064
  • Last updated
    2021-04-07 v1
  • Checksum
    652696D08446A6C5
MGVELTHPSSTGAIIQPDASFFNDLNGELGDKGFLVTSTEDLFHWARTGSLWWMTFGLACCAVEMIHVNMPRYDLERFGAAPRASPRQSDVMIVAGTLCNKMAPALRKVYDQMSEPKYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGIMQLQRKIRRIGTIER

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP022672
EMBL· GenBank· DDBJ
BCA58499.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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