A0A6S6AAU0 · G432_FUSSX

  • Protein
    Myb-like transcription factor
  • Gene
    g432
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Organism
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Transcription factor; part of the gene cluster that mediates the biosynthesis of 1233A, a natural compound known as an inhibitor of HMG-CoA synthase in the mevalonate pathway and with antibacterial and antifungal activities (PubMed:32139880).
Involved in hygromycin B-induced transcriptional control of the cluster (PubMed:32139880).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Myb-like transcription factor
  • Alternative names
    • 1233A biosynthesis cluster protein g432

Gene names

    • Name
      g432

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • RK97-94
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium

Accessions

  • Primary accession
    A0A6S6AAU0

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Impairs the ability to produce 1233A and 1233B.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004546311-382Myb-like transcription factor

Expression

Induction

Expression is increased upon exposure to hygromycin B.

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain1-57Myb-like 1
Domain58-108Myb-like 2
Domain109-160Myb-like 3
Compositional bias194-210Acidic residues
Region194-240Disordered
Compositional bias211-240Polar residues

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    382
  • Mass (Da)
    42,157
  • Last updated
    2020-12-02 v1
  • Checksum
    CDF30F83178262B8
MPRSPRRWTPEEDRVLLDKVKQLFSDGAKNDTTISWATVANALPDRNNKDCRKRWSKITGAKKGSWSLSEDEQLLEGVQKYGRQWAMVAKGVETRSADQCAKRWQHCLDPSLDRSEWRSDQDARLVAAVRRYGTNWKDIKKFEFPKRSTTNLKNRHITLFRQRNKAPGACPGSTETLGPGIDWWSMEQGMIDDMSMDASEDGDDAEDDQTPDSYTSISTSSFDDILGGSSSSPSAADTMTTASPDPYQYLLDWAVPSHADLVQAATSYYPSLDGFLGSTYDHNAKIDSSLGRDANGGNFIPGFPTQTPSQFESIDVSQISDGIVSGEPSRQGASRECRAASNVSSGPQMTLTIDNPDPQTMTGILEVLAKANSKVTISMNRE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias194-210Acidic residues
Compositional bias211-240Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LC516401
EMBL· GenBank· DDBJ
BBU37367.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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