A0A6Q8PG02 · A0A6Q8PG02_HUMAN
- ProteinLeucine rich repeat and sterile alpha motif containing 1
- GeneLRSAM1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids704 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A6Q8PG02
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 789 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 212 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 215 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 224 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 270 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 271 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 475 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 543 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 585 | PRIDE | Phosphoserine | ||||
Sequence: S |
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 263-295 | Disordered | ||||
Sequence: TQLLQQSSSQKDEILQTVKEEQSRLEQGLSEHQ | ||||||
Compositional bias | 276-295 | Basic and acidic residues | ||||
Sequence: ILQTVKEEQSRLEQGLSEHQ | ||||||
Coiled coil | 492-527 | |||||
Sequence: LSSLLQQLLKEKQQREEELREILTELEAKSETRQEN | ||||||
Domain | 559-613 | SAM | ||||
Sequence: LEELSAEHYLPIFAHHRLSLDLLSQMSPGDLAKVGVSEAGLQHEILRRVQELLDA | ||||||
Region | 623-646 | Disordered | ||||
Sequence: PMGEVVTPTAPQEPPESVRPSAPP | ||||||
Domain | 656-691 | RING-type | ||||
Sequence: CVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCR |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length704
- Mass (Da)81,605
- Last updated2020-12-02 v1
- Checksum3DAC1A87408DC61D
Computationally mapped potential isoform sequences
There are 17 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q6UWE0 | LRSM1_HUMAN | LRSAM1 | 723 | ||
A0A6Q8PFL5 | A0A6Q8PFL5_HUMAN | LRSAM1 | 653 | ||
A0A6Q8PFI6 | A0A6Q8PFI6_HUMAN | LRSAM1 | 420 | ||
A0A6Q8PFL1 | A0A6Q8PFL1_HUMAN | LRSAM1 | 254 | ||
A0A6Q8PG90 | A0A6Q8PG90_HUMAN | LRSAM1 | 173 | ||
A0A6Q8PFW1 | A0A6Q8PFW1_HUMAN | LRSAM1 | 432 | ||
A0A6Q8PFT9 | A0A6Q8PFT9_HUMAN | LRSAM1 | 663 | ||
A0A6Q8PGH9 | A0A6Q8PGH9_HUMAN | LRSAM1 | 149 | ||
A0A6Q8PGB2 | A0A6Q8PGB2_HUMAN | LRSAM1 | 750 | ||
A0A6Q8PGF7 | A0A6Q8PGF7_HUMAN | LRSAM1 | 708 | ||
A0A6Q8PGZ2 | A0A6Q8PGZ2_HUMAN | LRSAM1 | 165 | ||
A0A6Q8PGT8 | A0A6Q8PGT8_HUMAN | LRSAM1 | 638 | ||
A0A6Q8PH70 | A0A6Q8PH70_HUMAN | LRSAM1 | 428 | ||
A0A6Q8PGW1 | A0A6Q8PGW1_HUMAN | LRSAM1 | 690 | ||
A0A6Q8PEU7 | A0A6Q8PEU7_HUMAN | LRSAM1 | 85 | ||
A0A6Q8PF55 | A0A6Q8PF55_HUMAN | LRSAM1 | 236 | ||
A0A6Q8PHH6 | A0A6Q8PHH6_HUMAN | LRSAM1 | 407 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 276-295 | Basic and acidic residues | ||||
Sequence: ILQTVKEEQSRLEQGLSEHQ |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL445222 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |