A0A6Q8PF75 · A0A6Q8PF75_HUMAN
- ProteinD-ribitol-5-phosphate cytidylyltransferase
- GeneCRPPA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids315 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- CTP + D-ribitol 5-phosphate + H+ = CDP-L-ribitol + diphosphate
- CTP + D-ribose 5-phosphate + H+ = CDP-D-ribose + diphosphate
- CTP + D-ribulose 5-phosphate + H+ = CDP-D-ribulose + diphosphate
Pathway
Protein modification; protein glycosylation.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | D-ribitol-5-phosphate cytidylyltransferase activity | |
Biological Process | isoprenoid biosynthetic process | |
Biological Process | protein glycosylation |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameD-ribitol-5-phosphate cytidylyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A6Q8PF75
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Variants
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The viewer provides 389 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 147-294 | D-ribitol-5-phosphate cytidylyltransferase C-terminal | ||||
Sequence: QEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVTSEALGHAGRHLQQIILDQCYNFVCVNVTTSDFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVKERNILLYGLLISYPQDDQKLQESLRQGA |
Sequence similarities
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length315
- Mass (Da)35,551
- Last updated2020-12-02 v1
- ChecksumA929BB0FB0752870
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A4D126 | ISPD_HUMAN | CRPPA | 451 | ||
A0A6Q8PG39 | A0A6Q8PG39_HUMAN | CRPPA | 350 | ||
A0A6Q8PHI3 | A0A6Q8PHI3_HUMAN | CRPPA | 301 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC004741 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC005014 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC006035 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC073629 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC079155 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF458390 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |