A0A6Q8JR05 · A0A6Q8JR05_HUMAN

  • Protein
    FAT atypical cadherin 4
  • Gene
    FAT4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapical part of cell
Cellular Componentplasma membrane
Molecular Functioncalcium ion binding
Biological Processbranching involved in ureteric bud morphogenesis
Biological Processcerebral cortex development
Biological Processcondensed mesenchymal cell proliferation
Biological Processdigestive tract development
Biological Processfibroblast growth factor receptor signaling pathway
Biological Processheart morphogenesis
Biological Processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
Biological Processhippo signaling
Biological Processhomophilic cell adhesion via plasma membrane adhesion molecules
Biological Processinner ear receptor cell stereocilium organization
Biological ProcessNotch signaling pathway
Biological Processossification involved in bone maturation
Biological Processplasma membrane organization
Biological Processregulation of metanephric nephron tubule epithelial cell differentiation

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • FAT atypical cadherin 4

Gene names

    • Name
      FAT4

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A6Q8JR05

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane4504-4528Helical

Keywords

  • Cellular component

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 6,328 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Genetic variation databases

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Signal1-42UniProt
ChainPRO_502811778943-4983UniProt
Disulfide bond3852↔3861UniProt
Disulfide bond3890↔3899UniProt
Disulfide bond3928↔3937UniProt
Disulfide bond3966↔3975UniProt
Disulfide bond4190↔4199UniProt
Disulfide bond4455↔4464UniProt
Modified residue (large scale data)4657PRIDEPhosphoserine
Modified residue (large scale data)4688PRIDEPhosphoserine
Modified residue (large scale data)4704PRIDEPhosphoserine
Modified residue (large scale data)4718PRIDEPhosphoserine
Modified residue (large scale data)4757PRIDEPhosphoserine
Modified residue (large scale data)4784PRIDEPhosphoserine
Modified residue (large scale data)4878PRIDEPhosphoserine

Keywords

Proteomic databases

Expression

Gene expression databases

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain43-135Cadherin
Domain136-250Cadherin
Domain251-353Cadherin
Domain359-475Cadherin
Domain476-582Cadherin
Domain584-689Cadherin
Domain690-793Cadherin
Domain794-893Cadherin
Domain894-996Cadherin
Domain997-1100Cadherin
Domain1101-1210Cadherin
Domain1211-1315Cadherin
Domain1316-1420Cadherin
Domain1428-1529Cadherin
Domain1544-1629Cadherin
Domain1630-1740Cadherin
Domain1741-1841Cadherin
Domain1842-1944Cadherin
Domain1945-2051Cadherin
Domain2051-2154Cadherin
Domain2155-2259Cadherin
Domain2260-2364Cadherin
Domain2365-2468Cadherin
Domain2469-2569Cadherin
Domain2570-2671Cadherin
Domain2672-2775Cadherin
Domain2775-2874Cadherin
Domain2875-2985Cadherin
Domain2986-3091Cadherin
Domain3092-3196Cadherin
Domain3197-3300Cadherin
Domain3301-3406Cadherin
Domain3407-3512Cadherin
Domain3511-3622Cadherin
Domain3804-3862EGF-like
Domain3864-3900EGF-like
Domain3902-3938EGF-like
Domain3940-3976EGF-like
Domain3977-4161Laminin G
Domain4164-4200EGF-like
Domain4219-4400Laminin G
Domain4428-4465EGF-like
Compositional bias4536-4557Basic and acidic residues
Region4536-4586Disordered
Region4682-4715Disordered
Region4754-4858Disordered
Compositional bias4813-4827Basic and acidic residues
Region4871-4913Disordered
Compositional bias4875-4891Basic and acidic residues
Region4959-4983Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    4,983
  • Mass (Da)
    542,937
  • Last updated
    2020-12-02 v1
  • Checksum
    30FB2957BDC7EA61

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q6V0I7FAT4_HUMANFAT44981
A0A7P0T1I0A0A7P0T1I0_HUMANFAT43240

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias4536-4557Basic and acidic residues
Compositional bias4813-4827Basic and acidic residues
Compositional bias4875-4891Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC079835
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC092629
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC098865
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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