A0A6P4F3X9 · A0A6P4F3X9_DRORH
- Proteindual-specificity kinase
- GeneLOC108048765
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids812 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Cofactor
Protein has several cofactor binding sites:
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | actin cytoskeleton organization | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedual-specificity kinase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionA0A6P4F3X9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-231 | Protein kinase | ||||
Sequence: MVLKMNQLRANRPNMLREVQLLNKLSHANILSFMGVCVQEGQLHALTEYINGGSLEQLLANKEVVLSATQKIRLALGIAHGMSYVHDAGIFHRDLTSKNVLIRNLANDQYEAVVGDFGLAAKIPVKSRKSRLETVGSPYWVSPECLKGQWYDQTSDVFSFGIIQCEIIARIEADPDMMPRTASFGLDYLAFVELCPMDTPPVFLRLAFYCCLYDAKSRPTFHDALKKLTLL | ||||||
Region | 296-325 | Disordered | ||||
Sequence: EEGFRFPSKKSASAALPGTPNGSAGSNGFD | ||||||
Region | 359-389 | Disordered | ||||
Sequence: PMHTSPSDKARCHQMQRQRSSTHSPTPPRQL | ||||||
Compositional bias | 375-389 | Polar residues | ||||
Sequence: RQRSSTHSPTPPRQL | ||||||
Region | 547-603 | Disordered | ||||
Sequence: ISNAAPVAPPPTALPADEDDCEYCFSEGEDPDGGGNCADAESSSDDSAERPATVPTA |
Sequence similarities
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length812
- Mass (Da)87,004
- Last updated2020-12-02 v1
- Checksum24BCE04F428002A4
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A6P4FCW4 | A0A6P4FCW4_DRORH | LOC108048765 | 1076 | ||
A0A6P4F7S9 | A0A6P4F7S9_DRORH | LOC108048765 | 1075 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 375-389 | Polar residues | ||||
Sequence: RQRSSTHSPTPPRQL |
Keywords
- Technical term