A0A6P4AQK4 · A0A6P4AQK4_ZIZJJ

Function

function

Bifunctional aspartate kinase and homoserine dehydrogenase that catalyzes the first and the third steps toward the synthesis of lysine, methionine and threonine from aspartate.

Catalytic activity

Cofactor

a metal cation (UniProtKB | Rhea| CHEBI:25213 )

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.

GO annotations

AspectTerm
Molecular Functionaspartate kinase activity
Molecular FunctionATP binding
Molecular Functionhomoserine dehydrogenase activity
Molecular FunctionNADP binding
Biological Processhomoserine biosynthetic process
Biological Processlysine biosynthetic process via diaminopimelate
Biological Processmethionine biosynthetic process
Biological Processthreonine biosynthetic process

Keywords

Enzyme and pathway databases

    • UPA00034UER00015
    • UPA00050UER00063
    • UPA00051UER00462

Names & Taxonomy

Protein names

  • Submitted names
    • Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like

Gene names

    • Name
      LOC107423468

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Rosales > Rhamnaceae > Paliureae > Ziziphus

Accessions

  • Primary accession
    A0A6P4AQK4

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain414-489ACT
Domain495-572ACT

Sequence similarities

In the C-terminal section; belongs to the homoserine dehydrogenase family.
In the N-terminal section; belongs to the aspartokinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    918
  • Mass (Da)
    100,750
  • Last updated
    2020-12-02 v1
  • Checksum
    548ED32DAFAD1F1D
MASFSSAISNPRHVLSQKALAHDAKHMKICASHCSAFPLHFQRSPICRMSFISRLERKETRKPQISASVTDTTVGKSSEKVKLPKGDMWSVHKFGGTCVGSSERIKNVADIILNDDSERKLVVVSAMSKVTDMMYDLIYKAQSRDESYISALDAVLEKHRSTALDLLDGDELGSFLSQLHHDISNLKAMLRAIYIAGHATESFTDFVVGHGELWSAQLLSSLVRKNGVDCQWMDTREVLVVNPTSSNQVDPVYAESEQRLEKWYSKNQAKTIIATGFIASTPQNIPTTLKRDGSDFSSAIMGALLRARQVTIWTDVDGVYSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYDIPIIIRNIFNLSAPGTKICRAAADMDEVAQGLESYVKGFATIDNLALVNVEGTGMAGVPGTASAIFDAVKAVGANVIMISQASSEHSVCFAVPDKEVKAVAEALQSRFRQALDAGRLSQVQVIPNCSILAAVGQKMASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVLKREDCIRGLRAVHSRFYLSRTTIAVGIIGPGLIGGTLLDQLRDQTATLKEEFNIDLRVMGITGSRTMLLSDSGIDLARWRELLKEEGEKAVLEKFVHHVHENHFIPNTVLVDCTADSGIASHYNDWLRKGIHVVTPNKKANSGPLDQYLKLRALQRQSYTHYFYEATVGAGLPIISTLRGLLETGDRILRIEGIFSGTLSYIFNNFISGRTFSEVVAEAKQAGYTEPDPRDDLSGTDVRRKVIILARESGLKLELSDIPVESLVPEPLRACPSAEEFMQKLPQFDHDLATKRQIAEDAGEVLRYVGVVDVIKQKGEVQLRTYKKDHPFAQLSGSDNIIAFTTRRYKEQPLIVRGPGAGAEVTAGGVFSDILRLASYLGAPS

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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