A0A6P4AQK4 · A0A6P4AQK4_ZIZJJ
- ProteinBifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like
- GeneLOC107423468
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids918 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Bifunctional aspartate kinase and homoserine dehydrogenase that catalyzes the first and the third steps toward the synthesis of lysine, methionine and threonine from aspartate.
Catalytic activity
- ATP + L-aspartate = 4-phospho-L-aspartate + ADPThis reaction proceeds in the forward direction.
Cofactor
Pathway
Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | aspartate kinase activity | |
Molecular Function | ATP binding | |
Molecular Function | homoserine dehydrogenase activity | |
Molecular Function | NADP binding | |
Biological Process | homoserine biosynthetic process | |
Biological Process | lysine biosynthetic process via diaminopimelate | |
Biological Process | methionine biosynthetic process | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Rosales > Rhamnaceae > Paliureae > Ziziphus
Accessions
- Primary accessionA0A6P4AQK4
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 414-489 | ACT | ||||
Sequence: VEGTGMAGVPGTASAIFDAVKAVGANVIMISQASSEHSVCFAVPDKEVKAVAEALQSRFRQALDAGRLSQVQVIPN | ||||||
Domain | 495-572 | ACT | ||||
Sequence: AVGQKMASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVLKREDCIRGLRAVHSRFYLSRTTIAVGIIGPGLIGG |
Sequence similarities
In the C-terminal section; belongs to the homoserine dehydrogenase family.
In the N-terminal section; belongs to the aspartokinase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length918
- Mass (Da)100,750
- Last updated2020-12-02 v1
- Checksum548ED32DAFAD1F1D
Keywords
- Technical term