A0A6P1BUG0 · A0A6P1BUG0_9BRAD
- ProteinShikimate kinase
- GenearoK
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2488 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
Catalytic activity
- shikimate + ATP = 3-phosphoshikimate + ADP + H+
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Pathway
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 2308-2313 | ATP (UniProtKB | ChEBI) | |||
Binding site | 2312 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 2330 | substrate | |||
Binding site | 2376 | substrate | |||
Binding site | 2414 | ATP (UniProtKB | ChEBI) | |||
Binding site | 2450 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | ribonucleoprotein granule | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | RNA binding | |
Molecular Function | shikimate kinase activity | |
Biological Process | amino acid biosynthetic process | |
Biological Process | aromatic amino acid family biosynthetic process | |
Biological Process | chorismate biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | regulation of mitochondrial mRNA stability |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameShikimate kinase
- EC number
- Short namesSK
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Nitrobacteraceae > Bradyrhizobium
Accessions
- Primary accessionA0A6P1BUG0
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-20 | Polar residues | |||
Region | 1-248 | Disordered | |||
Compositional bias | 41-65 | Polar residues | |||
Compositional bias | 104-134 | Basic and acidic residues | |||
Compositional bias | 180-199 | Basic and acidic residues | |||
Compositional bias | 201-216 | Polar residues | |||
Sequence similarities
Belongs to the shikimate kinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,488
- Mass (Da)272,449
- Last updated2020-10-07 v1
- Checksum9747180AF5407B30
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-20 | Polar residues | |||
Compositional bias | 41-65 | Polar residues | |||
Compositional bias | 104-134 | Basic and acidic residues | |||
Compositional bias | 180-199 | Basic and acidic residues | |||
Compositional bias | 201-216 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VKHP01000304 EMBL· GenBank· DDBJ | NEV02056.1 EMBL· GenBank· DDBJ | Genomic DNA |