A0A6N9SVA4 · A0A6N9SVA4_9HYPH

  • Protein
    Pantothenate synthetase
  • Gene
    panC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.

Miscellaneous

The reaction proceeds by a bi uni uni bi ping pong mechanism.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site30-37ATP (UniProtKB | ChEBI)
Active site37Proton donor
Binding site61(R)-pantoate (UniProtKB | ChEBI)
Binding site61beta-alanine (UniProtKB | ChEBI)
Binding site147-150ATP (UniProtKB | ChEBI)
Binding site153(R)-pantoate (UniProtKB | ChEBI)
Binding site176ATP (UniProtKB | ChEBI)
Binding site184-187ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionpantoate-beta-alanine ligase activity
Biological Processpantothenate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pantothenate synthetase
  • EC number
  • Short names
    PS
  • Alternative names
    • Pantoate--beta-alanine ligase
    • Pantoate-activating enzyme

Gene names

    • Name
      panC
    • ORF names
      GTK09_00895

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 40Bstr34
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Aurantimonadaceae > Jiella

Accessions

  • Primary accession
    A0A6N9SVA4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the pantothenate synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    282
  • Mass (Da)
    30,682
  • Last updated
    2020-10-07 v1
  • Checksum
    2F10B6F87B7550B0
MERYDTIDALRAALGRARQTGRSIGLVPTMGYLHAGHLELVRRARAENDITVVSIFVNPTQFAPSEDFSTYPRDMERDLALLAQSGVDAVFTPGVEEMYPQPLQTTISLKPLGDILIGKVRPGHFSGVATVVAKLFNIVQPTRAYFGEKDFQQLTVIRRMVDDLNVPVEIVGVPTVREVDGLAMSSRNVRLSPQDRQAARVLSKALFEGAAMIEAGESDAAGILAKMTARIVAEPGVTLRSLDICDARDLAPVETIDRPVVVLVTAEVGPVLLIDQREARPA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAAMG010000001
EMBL· GenBank· DDBJ
NDW02973.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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