A0A6N8FTQ7 · A0A6N8FTQ7_9CHRO

Function

function

Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site44-51ATP (UniProtKB | ChEBI)
Active site51Proton donor
Binding site75(R)-pantoate (UniProtKB | ChEBI)
Binding site75beta-alanine (UniProtKB | ChEBI)
Binding site165-168ATP (UniProtKB | ChEBI)
Binding site171(R)-pantoate (UniProtKB | ChEBI)
Binding site194ATP (UniProtKB | ChEBI)
Binding site202-205ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function(d)CMP kinase activity
Molecular FunctionATP binding
Molecular Functionpantoate-beta-alanine ligase activity
Biological Processpantothenate biosynthetic process
Biological Processpyrimidine nucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional pantoate ligase/cytidylate kinase

Including 2 domains:

  • Recommended name
    Pantothenate synthetase
  • EC number
  • Short names
    PS
  • Alternative names
    • Pantoate--beta-alanine ligase
    • Pantoate-activating enzyme
  • Recommended name
    Cytidylate kinase
  • EC number
  • Short names
    CK
  • Alternative names
    • Cytidine monophosphate kinase
      (CMP kinase
      )

Gene names

    • Name
      panC/cmk
    • ORF names
      BWI75_08215

Organism names

  • Taxonomic identifier
  • Strain
    • 1H9
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Oscillatoriophycideae > Chroococcales > Chroococcaceae > Gloeocapsopsis > Gloeocapsopsis dulcis

Accessions

  • Primary accession
    A0A6N8FTQ7

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-295Pantoate--beta-alanine ligase
Region296-526Cytidylate kinase
Domain304-521Cytidylate kinase

Sequence similarities

Belongs to the cytidylate kinase family. Type 1 subfamily.
Belongs to the pantothenate synthetase family.
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
In the N-terminal section; belongs to the pantothenate synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    526
  • Mass (Da)
    57,878
  • Last updated
    2020-10-07 v1
  • Checksum
    EEAD9272099CEBBD
MRLFTTIAALRCYLDCRSADNHLTPEELSSGCSSSQSVGLVPTMGALHAGHLSLIQRARQENETVIVSIFVNPLQFGPNEDYQSYPRTLERDRELCKQVGVDALFVPTPAEMGIDKPSTFLTQVIPPIEMTSVLCGRSRPGHFQGVATIVTKLLNVVQPDRAYFGQKDGQQLAIIRRVVNDLNIPVEMIGCPIVRETSGLAMSSRNQYLTPAQREEAAVLYRSLQQAKQAFDTGEYFSKALIETVKKEVATASAVTLEYVELVHPLTLMPLEKIEESGMLAIAARVGTARLIDNVILQNRQPIIAIDGPAGAGKSTVARQVAAKLGLLYLDTGAMYRALTWLVLQLGISFDDCTAIAELASLSQIQLVPEVDLESPQRVWINNQEVTQAIRTIEVTSQVSAIAAQPAVRKALVQKQQAFGKEGGLVAEGRDIGTQVFPDADLKIFLTASVQERAKRRQQDFEQGQINISLTQLEKDIAERDKKDSTREVSPLQKAADAIEVQTDGKKVAEVIAEIIDYYHQRLSRQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NAPY01000010
EMBL· GenBank· DDBJ
MUL36331.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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