A0A6N7TK45 · A0A6N7TK45_9FIRM

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

TypeIDPosition(s)Description
Site12Important for substrate specificity
Active site69Proton acceptor
Site70Important for substrate specificity
Site152Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionnucleoside triphosphate diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • ORF names
      GKG36_01075

Organism names

Accessions

  • Primary accession
    A0A6N7TK45

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    185
  • Mass (Da)
    20,115
  • Last updated
    2020-10-07 v1
  • Checksum
    5DDD7DD338B8BF84
MMNLILASGSPRRRELLSLYTTNFTVCVSDFDESAVQAATPAHLVEQLARGKCLAVSAQHPGAVVIGCDTVVDVNGEVFGKPHSKEDAKRMLRALSGATHEVHTGVCISDGTRTESFVDSCRVTFFPLGEEEIDFYASTAEPYDKAGAYAIQGRAALWLDRIEGDYYTIMGLPVSRTVQLLAHFV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WKZJ01000001
EMBL· GenBank· DDBJ
MSD58553.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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