A0A6M9PMX3 · A0A6M9PMX3_9BURK
- ProteinRibonuclease 3
- Genernc
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids263 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
Catalytic activity
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 44 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 48 | ||||
Binding site | 117 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 120 | ||||
Binding site | 120 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | double-stranded RNA binding | |
Molecular Function | metal ion binding | |
Molecular Function | ribonuclease III activity | |
Molecular Function | rRNA binding | |
Biological Process | mRNA processing | |
Biological Process | regulation of gene expression | |
Biological Process | rRNA processing | |
Biological Process | tRNA processing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease 3
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Polynucleobacter
Accessions
- Primary accessionA0A6M9PMX3
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 9-131 | RNase III | |||
Domain | 158-228 | DRBM | |||
Region | 231-263 | Disordered | |||
Compositional bias | 247-263 | Basic and acidic residues | |||
Sequence similarities
Belongs to the ribonuclease III family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length263
- Mass (Da)28,928
- Last updated2020-10-07 v1
- Checksum5631E7BB77555FFA
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 247-263 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP028942 EMBL· GenBank· DDBJ | QKM64130.1 EMBL· GenBank· DDBJ | Genomic DNA |