A0A6M9PMX3 · A0A6M9PMX3_9BURK

Function

function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.

Catalytic activity

  • Endonucleolytic cleavage to 5'-phosphomonoester.
    EC:3.1.26.3 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

126320406080100120140160180200220240260
Type
IDPosition(s)Description
Binding site44Mg2+ (UniProtKB | ChEBI)
Active site48
Binding site117Mg2+ (UniProtKB | ChEBI)
Active site120
Binding site120Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functiondouble-stranded RNA binding
Molecular Functionmetal ion binding
Molecular Functionribonuclease III activity
Molecular FunctionrRNA binding
Biological ProcessmRNA processing
Biological Processregulation of gene expression
Biological ProcessrRNA processing
Biological ProcesstRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease 3
  • EC number
  • Alternative names
    • Ribonuclease III
      (RNase III
      )

Gene names

    • Name
      rnc
    • ORF names
      DCO17_02125

Organism names

  • Taxonomic identifier
  • Strain
    • MWH-UH21B
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Polynucleobacter

Accessions

  • Primary accession
    A0A6M9PMX3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain9-131RNase III
Domain158-228DRBM
Region231-263Disordered
Compositional bias247-263Basic and acidic residues

Sequence similarities

Belongs to the ribonuclease III family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    263
  • Mass (Da)
    28,928
  • Last updated
    2020-10-07 v1
  • Checksum
    5631E7BB77555FFA
MNARAVIETAPLQERLGYSFKKPELLNQALTHRSHSKKNNERLEFLGDSVLNCVVAEMLYERYSDLDEGDLSRVRANLVKQQALYEIAQTLSLSDYLRLGEGELKSGGFRRPSILADTLEAVTGAIFLDGGFDAAKTCLRKLYSIILSQVDPKTLGKDDKTLLQECLQSYQLPLPTYNVTGTSGAAHNQQFEVECLIPSLKVAVKGGGASRRAAEQSAAKSALLAVLKALPQDSRKPKKTRSAKKKAAKKEATEEQLYLKLKG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias247-263Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP028942
EMBL· GenBank· DDBJ
QKM64130.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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