A0A6M8UCE5 · A0A6M8UCE5_9GAMM

Function

function

Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

chloride (UniProtKB | Rhea| CHEBI:17996 )

Pathway

Organic acid metabolism; glycolate biosynthesis; glycolate from 2-phosphoglycolate: step 1/1.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site13Nucleophile
Binding site13Mg2+ (UniProtKB | ChEBI)
Binding site15Mg2+ (UniProtKB | ChEBI)
Binding site176Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionphosphoglycolate phosphatase activity
Biological Processcarbohydrate metabolic process
Biological Processglycolate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoglycolate phosphatase
  • EC number
  • Short names
    PGP
    ; PGPase

Gene names

    • ORF names
      PMPD1_0330

Organism names

Accessions

  • Primary accession
    A0A6M8UCE5

Proteomes

Interaction

Subunit

Monomer.

Family & Domains

Sequence similarities

Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    225
  • Mass (Da)
    23,976
  • Last updated
    2020-10-07 v1
  • Checksum
    7916192849BC3EEB
MAHFTNIRGLAFDLDGTLVDSAPGLADALGQALNAMDLPAPGVERVSTWIGNGADIMVERTLTWALNRKPEADEQRDTRVLFDKYYAATVNSGSTLFPHVAASLEKLAAHDLPLAIVTNKPTPFVAPLLETLGIARYFSLIIGGDDVVAKKPHPAPIFLVLGKFGLLPQELLFVGDSRNDILAAQAAGCPCVGMTFGYNYGESITTSNPNLALDDFNDLLPALGL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP054212
EMBL· GenBank· DDBJ
QKJ85310.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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