A0A6M5UKZ9 · A0A6M5UKZ9_9BURK

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Cu2+ (UniProtKB | Rhea| CHEBI:29036 )

Note: Binds 1 copper ion per subunit, denoted as copper B.
heme b (UniProtKB | Rhea| CHEBI:60344 )

heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups per subunit, denoted as high- and low-spin.

Pathway

Energy metabolism; oxidative phosphorylation.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site63Fe (UniProtKB | ChEBI) of heme b 1; low-spin (UniProtKB | ChEBI); axial binding residue
Binding site210Cu cation B (UniProtKB | ChEBI)
Binding site260Cu cation B (UniProtKB | ChEBI)
Binding site261Cu cation B (UniProtKB | ChEBI)
Binding site348Fe (UniProtKB | ChEBI) of heme b 2; high-spin (UniProtKB | ChEBI); axial binding residue
Binding site350Fe (UniProtKB | ChEBI) of heme b 1; low-spin (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncytochrome-c oxidase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processelectron transport coupled proton transport
Biological Processoxidative phosphorylation
Biological Processrespiratory electron transport chain

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    cytochrome-c oxidase
  • EC number

Gene names

    • Name
      ccoN
    • ORF names
      DCO17_07885

Organism names

  • Taxonomic identifier
  • Strain
    • MWH-UH21B
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Polynucleobacter

Accessions

  • Primary accession
    A0A6M5UKZ9

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-44Helical
Transmembrane64-84Helical
Transmembrane96-120Helical
Transmembrane135-153Helical
Transmembrane160-180Helical
Transmembrane206-228Helical
Transmembrane240-257Helical
Transmembrane277-297Helical
Transmembrane309-329Helical
Transmembrane349-368Helical
Transmembrane388-416Helical
Transmembrane436-459Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain20-479Cytochrome oxidase subunit I profile

Sequence similarities

Belongs to the heme-copper respiratory oxidase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    479
  • Mass (Da)
    54,146
  • Last updated
    2020-10-07 v1
  • Checksum
    263931EBC58C5F3E
MGLAVGSNQDTFNYRVVSQFAIVTVLWGIVGMLVGVILAAQLIWPEITFNIPWLSYGRLRPLHTNAVIFAFGGSALFATSYYIVQRTCQARLFSDKLAAFTFWGWQLVIVGAAITLPLGISTSKEYAELEWPLDLLITVVWVAYAIVFFGTIMKRKTKHIYVSNWFFGAYILTIAILHIFNNIEMPASLWKSYSAYAGVQDAMVQWWYGHNAVGFFLTTSFLGMMYYFIPKQAERPIYSYRLSIVHFWALNFTYMWAGPHHLQHTALPDWTQSLGMVFSLILLAPSWGGMINGIMTLSGAWHKLRRDPILKFLVVALSFYGMSTFEGSMMSIKTVNSLSHYTDWTIGHVHSGALGWVAMITIGSLYYLIPRLVGQKDMYSTKLIELHFWIATIGVVIYIAAMWIAGVMQGLMWRAFEPDGTLTYSFVESVKATYPFYVIRLLGGLCYLTGMLLMAYNVFKTVQGKKFVNAPIPTAIVAH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MK984228
EMBL· GenBank· DDBJ
QJW39076.1
EMBL· GenBank· DDBJ
Genomic DNA
CP028942
EMBL· GenBank· DDBJ
QKM65164.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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