A0A6M4JPA8 · A0A6M4JPA8_BACSU
- ProteinTriosephosphate isomerase
- GenetpiA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids253 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
Catalytic activity
- D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 9-11 | substrate | |||
Active site | 95 | Electrophile | |||
Active site | 167 | Proton acceptor | |||
Binding site | 173 | substrate | |||
Binding site | 213 | substrate | |||
Binding site | 234-235 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | triose-phosphate isomerase activity | |
Biological Process | gluconeogenesis | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTriosephosphate isomerase
- EC number
- Short namesTIM ; TPI
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillati > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus
Accessions
- Primary accessionA0A6M4JPA8
Subcellular Location
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 213 | Phosphoserine | |||
Keywords
- PTM
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length253
- Mass (Da)27,030
- Last updated2020-10-07 v1
- MD5 Checksum9A120A78B6F71A98215A1BA941926DB0
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP052842 EMBL· GenBank· DDBJ | QJP90092.1 EMBL· GenBank· DDBJ | Genomic DNA |