A0A6M4JFM4 · A0A6M4JFM4_BACSU

Function

function

Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.

Features

Showing features for binding site, site, active site.

135350100150200250300350
Type
IDPosition(s)Description
Binding site51-53substrate
Binding site94substrate
Site160Transition state stabilizer
Binding site199substrate
Active site240Proton donor
Binding site250-251substrate

GO annotations

AspectTerm
Molecular FunctionS-methyl-5-thioribose-1-phosphate isomerase activity
Biological ProcessL-methionine salvage from methylthioadenosine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylthioribose-1-phosphate isomerase
  • EC number
  • Short names
    M1Pi
    ; MTR-1-P isomerase
  • Alternative names
    • S-methyl-5-thioribose-1-phosphate isomerase

Gene names

    • Name
      mtnA
    • ORF names
      HIR78_07475

Organism names

Accessions

  • Primary accession
    A0A6M4JFM4

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    353
  • Mass (Da)
    38,860
  • Last updated
    2020-10-07 v1
  • MD5 Checksum
    9DB366319900AABCE69729EA2872F038
MTHSFAVPRSVEWKETAITILNQQKLPDETEYLELTTKEDVFDAIVTLKVRGAPAIGITAAFGLALAAKDIETDNVTEFRRRLEDIKQYLNSSRPTAINLSWALERLSHSVENAISVNEAKTNLVHEAIQIQVEDEETCRLIGQNALQLFKKGDRIMTICNAGSIATSRYGTALAPFYLAKQKDLGLHIYACETRPVLQGSRLTAWELMQGGIDVTLITDSMAAHTMKEKQISAVIVGADRIAKNGDTANKIGTYGLAILANAFDIPFFVAAPLSTFDTKVKCGADIPIEERDPEEVRQISGVRTAPSNVPVFNPAFDITPHDLISGIITEKGIMTGNYEEEIEQLFKGEKVH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP052842
EMBL· GenBank· DDBJ
QJP87866.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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