A0A6M3RI55 · A0A6M3RI55_AMBTS

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

135750100150200250300350
TypeIDPosition(s)Description
Binding site73Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site87Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site172Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site186Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site191a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial respiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      CYTB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Parasitiformes > Ixodida > Ixodoidea > Ixodidae > Amblyomminae > Amblyomma

Accessions

  • Primary accession
    A0A6M3RI55

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-46Helical
Transmembrane67-88Helical
Transmembrane100-123Helical
Transmembrane135-156Helical
Transmembrane168-190Helical
Transmembrane222-241Helical
Transmembrane261-294Helical
Transmembrane315-333Helical

Keywords

Interaction

Subunit

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-199Cytochrome b/b6 N-terminal region profile
Domain200-357Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    357
  • Mass (Da)
    41,512
  • Last updated
    2020-10-07 v1
  • Checksum
    29D4EA9AE24CFA53
MMKLMNPLINIPSPSNISYLWNFGSLLGLCLLIQILTGLFLAMNFSSDIKTAFQMISHIQRDVNFGWLIRSVHANGASFFFIFIYIHISRGIYYSSFFFIKIWMSGILIIFMLMMTAFLGYILPWGQMSFWGATVITNLISAIPYLGQSITLWIWGGFSVDNNTLIRFFSLHFIFPFILMFLTLIHIMFLHEKGSSNPMGISMNIDKIPFHPYFSIKDLQGIMIFLIPFLMTILLFPYIMMDAENFIMANPMVTPPHIQPEWYFLFAYAILRSIPSKLGGVVALIMSIMIIAFLPFFLKNKISSLYYNNFDKFKFWMLVNTFLLLTFLGAMPIEYPYDTMSKITTSLYFFIFLLMFT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MT029329
EMBL· GenBank· DDBJ
QJD22109.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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