A0A6J6B649 · A0A6J6B649_9ZZZZ
- ProteinNicotinamide nucleotide repair protein
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids467 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
Catalytic activity
- (6R)-NADHX = (6S)-NADHX
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ADP-dependent NAD(P)H-hydrate dehydratase activity | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | NADHX epimerase activity | |
Molecular Function | NADPHX epimerase activity | |
Biological Process | metabolite repair |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNicotinamide nucleotide repair protein
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageunclassified sequences > metagenomes > ecological metagenomes
Accessions
- Primary accessionA0A6J6B649
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 10-180 | YjeF N-terminal | |||
Domain | 187-458 | YjeF C-terminal | |||
Sequence similarities
In the C-terminal section; belongs to the NnrD/CARKD family.
In the N-terminal section; belongs to the NnrE/AIBP family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length467
- Mass (Da)48,825
- Last updated2020-10-07 v1
- MD5 ChecksumC86F46D3E054824F070C6AC1A1297704
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAEZSL010000014 EMBL· GenBank· DDBJ | CAB4534164.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CAEZUK010000006 EMBL· GenBank· DDBJ | CAB4589856.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CAEZZV010000087 EMBL· GenBank· DDBJ | CAB4779609.1 EMBL· GenBank· DDBJ | Genomic DNA |