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A0A6J6B649 · A0A6J6B649_9ZZZZ

  • Protein
    Nicotinamide nucleotide repair protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.

Catalytic activity

Cofactor

K+ (UniProtKB | Rhea| CHEBI:29103 )

GO annotations

AspectTerm
Molecular FunctionADP-dependent NAD(P)H-hydrate dehydratase activity
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNADHX epimerase activity
Molecular FunctionNADPHX epimerase activity
Biological Processmetabolite repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nicotinamide nucleotide repair protein
  • EC number

Gene names

    • ORF names
      UFOPK1421_00219
      , UFOPK1820_00089
      , UFOPK2921_00781

Organism names

Accessions

  • Primary accession
    A0A6J6B649

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-180YjeF N-terminal
Domain187-458YjeF C-terminal

Sequence similarities

In the C-terminal section; belongs to the NnrD/CARKD family.
In the N-terminal section; belongs to the NnrE/AIBP family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    467
  • Mass (Da)
    48,825
  • Last updated
    2020-10-07 v1
  • MD5 Checksum
    C86F46D3E054824F070C6AC1A1297704
MRPVLTPKQMRVLDSETVTAGTPIDVLIGRAGAAVARTAKRMMGGLYGRTVVVVVGKGNNGADGRMAARLLADQGVRVHVLDAQQMPLRLPVSDLIIDAAFGTGFRGEWNPPATHGIPVLAVDIPSGVDGLTGLAVGDTWQATRTVTFVALKPGLLLGVGRALSGDIELIDIGINLGMGNVDINEVELADVSAWIPARPFDSHKWKTGLYALAGSTGMMGAANLSVAAAMRCGAGIVHLASPGIVHDRTTPTEVVRRSLSAFSWSEDVLEDVHRFKSMVVGPGLGRDEGTVSETRRVIAEAQVPMVIDGDGLFAVAWGGDGARNIVRTRSAETVLTPHDGEYQTLLGYAPSPDRIASARRLAIDTNCVCLLKGTTTVIAEPSGEVLMVTNGDQKLATAGTGDVLAGIIGGLMAQGLEAFHAAACGAWIHGHAASLFSFDEGLIASDLLDLIASALSEIRRVAKQDER

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAEZSL010000014
EMBL· GenBank· DDBJ
CAB4534164.1
EMBL· GenBank· DDBJ
Genomic DNA
CAEZUK010000006
EMBL· GenBank· DDBJ
CAB4589856.1
EMBL· GenBank· DDBJ
Genomic DNA
CAEZZV010000087
EMBL· GenBank· DDBJ
CAB4779609.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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