A0A6J4K9M5 · A0A6J4K9M5_9BACT

Function

function

Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site233L-serine (UniProtKB | ChEBI)
Binding site233-235L-serine (UniProtKB | ChEBI)
Binding site264L-serine (UniProtKB | ChEBI)
Binding site264-266ATP (UniProtKB | ChEBI)
Binding site287L-serine (UniProtKB | ChEBI)
Binding site351-354ATP (UniProtKB | ChEBI)
Binding site385L-serine (UniProtKB | ChEBI)
Binding site387L-serine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionserine-tRNA ligase activity
Biological Processselenocysteine biosynthetic process
Biological Processseryl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine--tRNA ligase
  • EC number
  • Alternative names
    • Seryl-tRNA synthetase
      (SerRS
      )
    • Seryl-tRNA(Ser/Sec) synthetase

Gene names

    • Name
      serS
    • ORF names
      AVDCRST_MAG68-323

Organism names

Accessions

  • Primary accession
    A0A6J4K9M5

Subcellular Location

Keywords

Interaction

Subunit

Homodimer. The tRNA molecule binds across the dimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain174-412Aminoacyl-transfer RNA synthetases class-II family profile

Domain

Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    431
  • Mass (Da)
    47,454
  • Last updated
    2020-10-07 v1
  • Checksum
    E9107E4B6924C4E5
MLDLQQIRHDPEAVRARLAARGNPAETDAAVERLGTLDAERRALVSEVDGLKGRRNQVSREVGERKRRGEDADALVAEMRAVGDRIAEIDVRVRAVEEERDSILLRIPNATDPSVPHGGEEANAVVRTWGEPRSLAFTARPHWELAAELGMLDLAAGARVSGSGFPVYRGIGARLQRALINFMLDLHTTEHGYTEIEPPFLVGRDAMTGTGQLPKFEDDAYRIESDDLFLIPTAEVPVTNLHRDELLAADQLPIAYTAYSPCFRREAGSAGKDTRGLLRLHQFDKVEMVRFERPEASDEALERLLGQAERVLQLLELPYRVLLLAAGDTGFSSAKTYDLEVWAPGVERWLEVSSCSNFRDFQARRAGIRFRPEAGAKPEFVHTLNGSGVALPRTVVALIENGQREDGSVTVPEALRPYLGTDRIAAPGGAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CADCTW010000022
EMBL· GenBank· DDBJ
CAA9299844.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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