A0A6I8RR90 · A0A6I8RR90_XENTR
- ProteinCAAX prenyl protease
- Genezmpste24
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids458 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Proteolytically removes the C-terminal three residues of farnesylated proteins.
Catalytic activity
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 318 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 319 | ||||
Binding site | 322 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 398 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 402 | Proton donor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | metal ion binding | |
Molecular Function | metalloendopeptidase activity | |
Biological Process | CAAX-box protein processing |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCAAX prenyl protease
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Silurana
Accessions
- Primary accessionA0A6I8RR90
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 64-89 | Helical | |||
Transmembrane | 110-131 | Helical | |||
Transmembrane | 158-176 | Helical | |||
Transmembrane | 183-203 | Helical | |||
Transmembrane | 332-350 | Helical | |||
Transmembrane | 357-379 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-18 | ||||
Chain | PRO_5031509715 | 19-458 | CAAX prenyl protease | ||
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length458
- Mass (Da)52,320
- Last updated2021-06-02 v2
- MD5 ChecksumBCDBED2E6F2F8971B9B2ED437A3CB398