A0A6I8RHW9 · A0A6I8RHW9_XENTR
- ProteinSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
- Genesdha
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids622 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Catalytic activity
- (R)-malate + a quinone = enol-oxaloacetate + a quinolThis reaction proceeds in the forward direction.
- (S)-malate + a quinone = enol-oxaloacetate + a quinolThis reaction proceeds in the forward direction.
Cofactor
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 300 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | succinate dehydrogenase (quinone) activity | |
Biological Process | electron transport chain | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Silurana
Accessions
- Primary accessionA0A6I8RHW9
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 59 | Tele-8alpha-FAD histidine | |||
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 23-417 | FAD-dependent oxidoreductase 2 FAD binding | |||
Domain | 474-622 | Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal | |||
Sequence similarities
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length622
- Mass (Da)67,914
- Last updated2021-06-02 v2
- Checksum8D517DB0DCC93661