A0A6I8RHW9 · A0A6I8RHW9_XENTR

Function

function

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site300Proton acceptor

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionsuccinate dehydrogenase (quinone) activity
Biological Processelectron transport chain
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  • EC number

Gene names

    • Name
      sdha

Organism names

Accessions

  • Primary accession
    A0A6I8RHW9

Organism-specific databases

Subcellular Location

Mitochondrion inner membrane
; Peripheral membrane protein

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue59Tele-8alpha-FAD histidine

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain23-417FAD-dependent oxidoreductase 2 FAD binding
Domain474-622Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal

Sequence similarities

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    622
  • Mass (Da)
    67,914
  • Last updated
    2021-06-02 v2
  • Checksum
    8D517DB0DCC93661
QTGGGATERGISTQYPVVDHDFDAVVVGAGGAGLRAAFGLSEAGFNTACITKLFPTRSHTVAAQGGINAALGNMEDDDWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVIELENYGMPFSRTEQGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCMEDGSIHRFRAKNTVIATGGYGRTFFSCTSAHTCTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSEGERFMERYAPVAKDLASRDVVSRSMTIEIREGRGCGKDKDHVYLQLHHLPPSQLASRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITHVNGEDRVVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALSIAESCKPGEPVPSIKENAGEESVANLDKLRFTNGSTRTSELRINMQKTMQNHAAVFRTGSVLKEGCEKLSAINSTMDDIKTFDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKSFSEHWRKHTLSYVDGKGKVSLEYRPVIDTTLNEDCVSVPPAIRSY

Genome annotation databases

Similar Proteins

Disclaimer

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