A0A6I8NPF5 · A0A6I8NPF5_ORNAN

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Molecular Functioncytokine activity
Molecular Functionhormone activity
Molecular Functionsignaling receptor binding
Biological Processcell population proliferation
Biological Processpositive regulation of ERK1 and ERK2 cascade
Biological Processpositive regulation of hematopoietic stem cell proliferation
Biological Processthrombopoietin-mediated signaling pathway

Keywords

  • Molecular function

Names & Taxonomy

Protein names

  • Recommended name
    Thrombopoietin

Gene names

    • Name
      THPO

Organism names

Accessions

  • Primary accession
    A0A6I8NPF5

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-23
ChainPRO_502625039424-330Thrombopoietin

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region171-330Disordered
Compositional bias266-298Polar residues
Compositional bias299-315Pro residues
Compositional bias316-330Polar residues

Sequence similarities

Belongs to the EPO/TPO family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    330
  • Mass (Da)
    34,102
  • Last updated
    2020-08-12 v1
  • Checksum
    EED5639115839E6D
MELTGLLLVALLLLPARLAFTSSAPACDPRLLNKLLRDARALQSRLSQCPDLSPLPLPVLLPAVDFSLREWKAKTEQIKGQEVLGAVALLMEGVGAAQGQLETNCLSRLLGQLSGQARLLFGALQGLLGAQPLPQDRVTAHRDPDAIFQNFWQLLVGKVRFLLHGPTLCARRGHPVPSPANGLLRPSAGRSGRGPPDRTPGPRATTPGLADPASGLPGRASALLNVTSGPVGPASGPLPNMTFGPSERAPGPPPVTPPLRDNATGFSGRTPGSLPSLPSNTDGFPRLSYQASGSPTPLTGLPAPSPNPTVPMPSSSTPLASPSATTPGSF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias266-298Polar residues
Compositional bias299-315Pro residues
Compositional bias316-330Polar residues

Keywords

Genome annotation databases

Similar Proteins

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