A0A6I8N8X4 · A0A6I8N8X4_ORNAN

Function

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Features

Showing features for binding site.

131520406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site148Fe cation (UniProtKB | ChEBI)
Binding site153Fe cation (UniProtKB | ChEBI)
Binding site193Fe cation (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functioniron ion binding
Molecular Functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
Biological Processaromatic amino acid metabolic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Tyrosine hydroxylase

Gene names

    • Name
      TH

Organism names

Accessions

  • Primary accession
    A0A6I8N8X4

Proteomes

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain51-315Biopterin-dependent aromatic amino acid hydroxylase family profile

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    315
  • Mass (Da)
    35,948
  • Last updated
    2020-08-12 v1
  • MD5 Checksum
    ACD3F7796CB1DE8A1FF926B210A82ECB
SDLTISELDRCHHLVTKFDPDLDLDHPGFSDQAYRQRRKMVAEIAFQYKQREVYTTLKSLYPTHACSEHLEALDLLEKFSGYSENNIPQLEDVSRFLKDRTGFQLRPVAGLLSARDFLSSLAFRVFQCTQYIRHSSSPMHSPEPDCCHELLGHVPMLADWTFAQFSQDIGLASLGATDEEIEKLSTLYWFTVEFGLCKQNGVIKAYGAGLLSSYGELLHALSDEPEIREFDPETVSVQPYQDQTYQPVYFVSESFSDAKDKLRNYASGIRRPFSVKYDPHTQAVEVLDSPQKIRLFLDGLREELHSLAQALNAFS

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A6I8P676A0A6I8P676_ORNANTH470
A0A6I8NEJ7A0A6I8NEJ7_ORNANTH212
A0A6I8N2F0A0A6I8N2F0_ORNANTH322

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help