A0A6I4NVR0 · A0A6I4NVR0_9FLAO

Function

function

Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site125-126NAD+ (UniProtKB | ChEBI)
Binding site203NAD+ (UniProtKB | ChEBI)
Binding site268NAD+ (UniProtKB | ChEBI)
Binding site395NAD+ (UniProtKB | ChEBI)
Binding site583NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionurocanate hydratase activity
Biological ProcessL-histidine catabolic process to glutamate and formamide
Biological ProcessL-histidine catabolic process to glutamate and formate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Urocanate hydratase
  • EC number
  • Short names
    Urocanase
  • Alternative names
    • Imidazolonepropionate hydrolase

Gene names

    • Name
      hutU
    • ORF names
      GON26_12095

Organism names

Accessions

  • Primary accession
    A0A6I4NVR0

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain84-210Urocanase N-terminal
Domain213-427Urocanase Rossmann-like
Domain433-636Urocanase C-terminal

Sequence similarities

Belongs to the urocanase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    658
  • Mass (Da)
    73,445
  • Last updated
    2020-08-12 v1
  • Checksum
    8BA49E63927891C9
MTFKEQIQQGIPSVLPSKKQYDLAINHAPKRKEILSAEEKKLALKNALRYFDAQHHAELLPEFSEELETYGRIYMYRLRPDYKMYARPIDEYPGKSVQAKAIMHMIQNNLDYAVAQHPHELITYGGNGAVFQNWAQYLLTMQYLSEMTDEQTLTMYSGHPMGLFPSHKEAPRVVVTNGMVIPNYSKPDDWEKMNALGVSQYGQMTAGSYMYIGPQGIVHGTTITVLNGFRKIKKNPEGNLFVTSGLGGMSGAQPKAGNIAGCITVCAEVNPKITKIRHEQGWINEIVTSTEELVERVNSAKANKEIVSIAYLGNVVDVWETFDKENIQIDLGSDQTSLHNPWAGGYYPVGISFEEANEMMANNPDLFKEKVQETLRRHAAAINKHTAKGTYFFDYGNAFLLEASRAGADVMAENNIDFKYPSYVQDIMGPMCFDYGFGPFRWVCTSGKPEDLQKTDAIASQVLEEMAKTAPDEIQQQMQDNIKWIKGAQENKLVVGSQARILYADAEGRIKIAEAFNQAIAKGEIGTVVLGRDHHDVSGTDSPYRETSNIYDGSRFTADMAIQNVIGDSFRGATWVSIHNGGGVGWGEVINGGFGMVLDGSKEASKRLASMLFWDVNNGISRRSWARNEEAIFAIKRAMEVEPLLKVTLPNIVDENLF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WSTB01000006
EMBL· GenBank· DDBJ
MWB95104.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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