A0A6I1EHX9 · A0A6I1EHX9_9BURK

  • Protein
    7-cyano-7-deazaguanine synthase
  • Gene
    queC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ0).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site20-30ATP (UniProtKB | ChEBI)
Binding site208Zn2+ (UniProtKB | ChEBI)
Binding site223Zn2+ (UniProtKB | ChEBI)
Binding site226Zn2+ (UniProtKB | ChEBI)
Binding site229Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionligase activity, forming carbon-nitrogen bonds
Molecular Functionzinc ion binding
Biological Processqueuosine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    7-cyano-7-deazaguanine synthase
  • EC number
  • Alternative names
    • 7-cyano-7-carbaguanine synthase
    • PreQ(0) synthase
    • Queuosine biosynthesis protein QueC

Gene names

    • Name
      queC
    • ORF names
      GBM95_10295

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ASD393
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Sutterellaceae > Sutterella

Accessions

  • Primary accession
    A0A6I1EHX9

Proteomes

Family & Domains

Sequence similarities

Belongs to the QueC family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    245
  • Mass (Da)
    27,340
  • Last updated
    2020-08-12 v1
  • Checksum
    AB8DBF60514B88F2
MTEFSDIASAGRDMAALVLFSGGQDSTTCLGWALERFGRVETVGVDYGQRHQAELVCRGKVLEKMRAMKPSWAERLGEDHMLSLPVLGEVADCALTDERRIAFESSGLPNTFVPGRNLLFFTLAAAIAYRRGARVLVGGMCETDYSGYPDCRDNTLKSLQVTLSLGLDAPIILETPLMRLTKAETWELAERTGSDEFVKLVRDETHTCYMGDHEHHHAWGWGCGECPACRLREKGWEEWSGSKRF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WEHX01000102
EMBL· GenBank· DDBJ
KAB7654451.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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