A0A6H5HQQ7 · A0A6H5HQQ7_9HEMI
- ProteinATP-dependent DNA helicase PIF1
- GenePIF1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1803 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
May be involved in the turnover of nuclear polyadenylated (pA+) RNA.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Cofactor
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Molecular Function | 5'-3' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | DNA binding | |
Molecular Function | hydrolase activity | |
Molecular Function | metal ion binding | |
Molecular Function | RNA binding | |
Biological Process | DNA recombination | |
Biological Process | DNA repair | |
Biological Process | mitochondrial genome maintenance | |
Biological Process | telomere maintenance |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent DNA helicase PIF1
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Heteroptera > Panheteroptera > Cimicomorpha > Miridae > Dicyphina > Nesidiocoris
Accessions
- Primary accessionA0A6H5HQQ7
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 105-126 | Disordered | ||||
Sequence: REPPPPAVGLPEEAERKSLKET | ||||||
Compositional bias | 155-234 | Basic and acidic residues | ||||
Sequence: RRDTDKHVRKSDSDKDERPPPPPSRRVRRRGSSPSPDRRRSRSRSFDRRRSRSRERERGRAWRNKSPPPRRYERSRRSFS | ||||||
Region | 155-325 | Disordered | ||||
Sequence: RRDTDKHVRKSDSDKDERPPPPPSRRVRRRGSSPSPDRRRSRSRSFDRRRSRSRERERGRAWRNKSPPPRRYERSRRSFSKSPQPRRLKSGSPQVKRISRRSYSKSPHRRYSSRSPQGKRTKYRNRSPPHSRSWTRSRSRSPLGGRDRKDVAIGLSPRENSHGDTDTRGLQ | ||||||
Compositional bias | 238-254 | Polar residues | ||||
Sequence: QPRRLKSGSPQVKRISR | ||||||
Compositional bias | 255-287 | Basic residues | ||||
Sequence: RSYSKSPHRRYSSRSPQGKRTKYRNRSPPHSRS | ||||||
Compositional bias | 295-319 | Basic and acidic residues | ||||
Sequence: SPLGGRDRKDVAIGLSPRENSHGDT | ||||||
Domain | 335-363 | C3H1-type | ||||
Sequence: GPYTRRCRDFDEQGFCIRGDLCPYDHGAD | ||||||
Zinc finger | 335-363 | C3H1-type | ||||
Sequence: GPYTRRCRDFDEQGFCIRGDLCPYDHGAD | ||||||
Compositional bias | 594-609 | Polar residues | ||||
Sequence: NNANNENKQENAPPTT | ||||||
Region | 594-619 | Disordered | ||||
Sequence: NNANNENKQENAPPTTRPSIMERLGD | ||||||
Region | 655-681 | Disordered | ||||
Sequence: YIPSAMKKDQPKEKPAEKDQTAQENKT | ||||||
Compositional bias | 661-681 | Basic and acidic residues | ||||
Sequence: KKDQPKEKPAEKDQTAQENKT | ||||||
Compositional bias | 1314-1329 | Polar residues | ||||
Sequence: VSPLSSKDVQRFKNSQ | ||||||
Region | 1314-1350 | Disordered | ||||
Sequence: VSPLSSKDVQRFKNSQSSQDDSKKRLREEESKGSQGS | ||||||
Compositional bias | 1330-1348 | Basic and acidic residues | ||||
Sequence: SSQDDSKKRLREEESKGSQ |
Sequence similarities
Belongs to the helicase family. PIF1 subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,803
- Mass (Da)201,430
- Last updated2020-08-12 v1
- Checksum4DCA6C0E19A137BC
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 155-234 | Basic and acidic residues | ||||
Sequence: RRDTDKHVRKSDSDKDERPPPPPSRRVRRRGSSPSPDRRRSRSRSFDRRRSRSRERERGRAWRNKSPPPRRYERSRRSFS | ||||||
Compositional bias | 238-254 | Polar residues | ||||
Sequence: QPRRLKSGSPQVKRISR | ||||||
Compositional bias | 255-287 | Basic residues | ||||
Sequence: RSYSKSPHRRYSSRSPQGKRTKYRNRSPPHSRS | ||||||
Compositional bias | 295-319 | Basic and acidic residues | ||||
Sequence: SPLGGRDRKDVAIGLSPRENSHGDT | ||||||
Compositional bias | 594-609 | Polar residues | ||||
Sequence: NNANNENKQENAPPTT | ||||||
Compositional bias | 661-681 | Basic and acidic residues | ||||
Sequence: KKDQPKEKPAEKDQTAQENKT | ||||||
Compositional bias | 1314-1329 | Polar residues | ||||
Sequence: VSPLSSKDVQRFKNSQ | ||||||
Compositional bias | 1330-1348 | Basic and acidic residues | ||||
Sequence: SSQDDSKKRLREEESKGSQ |
Keywords
- Technical term