A0A6H0Y755 · A0A6H0Y755_CLAMG
- ProteinVoltage-dependent R-type calcium channel subunit alpha-1E
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1882 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | neuronal cell body | |
Cellular Component | synapse | |
Cellular Component | voltage-gated calcium channel complex | |
Molecular Function | high voltage-gated calcium channel activity | |
Molecular Function | metal ion binding | |
Biological Process | calcium ion import across plasma membrane | |
Biological Process | chemical synaptic transmission |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Siluriformes > Clariidae > Clarias
Accessions
- Primary accessionA0A6H0Y755
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 93-110 | Helical | ||||
Sequence: FEYMILATIIANCIVLAL | ||||||
Transmembrane | 131-152 | Helical | ||||
Sequence: PYFIGMFCFEAGIKIVALGFVF | ||||||
Transmembrane | 164-184 | Helical | ||||
Sequence: VMDFIVVLSGILATAEAHMNI | ||||||
Transmembrane | 223-242 | Helical | ||||
Sequence: LLQIGLLLFFAILMFAIIGL | ||||||
Transmembrane | 302-323 | Helical | ||||
Sequence: ILFAVLTVFQCITMEGWTTVLY | ||||||
Transmembrane | 335-357 | Helical | ||||
Sequence: WLYFIPLIIIGSFFVLNLVLGVL | ||||||
Transmembrane | 484-503 | Helical | ||||
Sequence: TFYWTVLGLVALNTICVAIV | ||||||
Transmembrane | 515-532 | Helical | ||||
Sequence: LYYAEFLFLGLFLTEMFL | ||||||
Transmembrane | 610-632 | Helical | ||||
Sequence: IISLLFLLFLFIVVFALLGMQLF | ||||||
Transmembrane | 687-709 | Helical | ||||
Sequence: IYFIVLTLFGNYTLLNVFLAIAV | ||||||
Transmembrane | 1083-1102 | Helical | ||||
Sequence: LRYFEMCILLVIAASSIALA | ||||||
Transmembrane | 1155-1174 | Helical | ||||
Sequence: ILDFIVVVGALVAFALTNVL | ||||||
Transmembrane | 1220-1242 | Helical | ||||
Sequence: VFNILIVYKLFMFIFAVIAVQLF | ||||||
Transmembrane | 1332-1357 | Helical | ||||
Sequence: IFYVIYFVVFPFFFVNIFVALIIITF | ||||||
Transmembrane | 1413-1432 | Helical | ||||
Sequence: YTVLTMITLNTIVLMMKYYS | ||||||
Transmembrane | 1444-1466 | Helical | ||||
Sequence: LNTAFTVLFSIECVLKILAFGFV | ||||||
Transmembrane | 1534-1559 | Helical | ||||
Sequence: LPYVCLLIAMLFFIYAIIGMQVFGNI | ||||||
Transmembrane | 1626-1650 | Helical | ||||
Sequence: AYFYFVSFIFFSSFLMLNLFVAVIM |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 11-41 | Disordered | ||||
Sequence: AHGVLDGGSERSRTREPPPPSSSTGGVSPVF | ||||||
Compositional bias | 25-41 | Polar residues | ||||
Sequence: REPPPPSSSTGGVSPVF | ||||||
Coiled coil | 705-732 | |||||
Sequence: LAIAVDNLANAQELTKDEEEEEEAFNQK | ||||||
Region | 816-989 | Disordered | ||||
Sequence: EPSMEEQNVSASLPDPPESETPDNKDPCRNGSQAHTEISTTDQLLDPLDPAKEEQDIDNAQVSGNTPEELQDKNHLSVRRLNGERRQRGTRKYSKYGKHSKHRTSETHHERHDEPNAHERSRSASRTRTESEEEDEKRKSNNNGGVSQDERTAEESDLAAVSEPATLQISDSTT | ||||||
Compositional bias | 818-832 | Polar residues | ||||
Sequence: SMEEQNVSASLPDPP | ||||||
Compositional bias | 841-858 | Polar residues | ||||
Sequence: DPCRNGSQAHTEISTTDQ | ||||||
Compositional bias | 887-905 | Basic and acidic residues | ||||
Sequence: DKNHLSVRRLNGERRQRGT | ||||||
Compositional bias | 906-920 | Basic residues | ||||
Sequence: RKYSKYGKHSKHRTS | ||||||
Compositional bias | 921-972 | Basic and acidic residues | ||||
Sequence: ETHHERHDEPNAHERSRSASRTRTESEEEDEKRKSNNNGGVSQDERTAEESD | ||||||
Region | 1029-1061 | Disordered | ||||
Sequence: ELSTITAANSKELEASKSEKEDEEAANRSRTPP | ||||||
Compositional bias | 1041-1057 | Basic and acidic residues | ||||
Sequence: LEASKSEKEDEEAANRS | ||||||
Domain | 1787-1821 | Voltage-dependent calcium channel alpha-1 subunit IQ | ||||
Sequence: ASDMTIGKIYAAMMIMDYYKQNKAKKLKQQLEEQK |
Sequence similarities
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length1,882
- Mass (Da)214,673
- Last updated2020-08-12 v1
- ChecksumD90CD8A75A7531E9
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 25-41 | Polar residues | ||||
Sequence: REPPPPSSSTGGVSPVF | ||||||
Compositional bias | 818-832 | Polar residues | ||||
Sequence: SMEEQNVSASLPDPP | ||||||
Compositional bias | 841-858 | Polar residues | ||||
Sequence: DPCRNGSQAHTEISTTDQ | ||||||
Compositional bias | 887-905 | Basic and acidic residues | ||||
Sequence: DKNHLSVRRLNGERRQRGT | ||||||
Compositional bias | 906-920 | Basic residues | ||||
Sequence: RKYSKYGKHSKHRTS | ||||||
Compositional bias | 921-972 | Basic and acidic residues | ||||
Sequence: ETHHERHDEPNAHERSRSASRTRTESEEEDEKRKSNNNGGVSQDERTAEESD | ||||||
Compositional bias | 1041-1057 | Basic and acidic residues | ||||
Sequence: LEASKSEKEDEEAANRS | ||||||
Non-terminal residue | 1882 | |||||
Sequence: R |