A0A6H0EXW5 · A0A6H0EXW5_9ECHN

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

138050100150200250300350
TypeIDPosition(s)Description
Binding site84Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site98Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site183Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site197Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site202a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      CYTB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Echinodermata > Eleutherozoa > Echinozoa > Holothuroidea > Aspidochirotacea > Aspidochirotida > Holothuriidae > Holothuria

Accessions

  • Primary accession
    A0A6H0EXW5

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane30-54Helical
Transmembrane88-108Helical
Transmembrane114-134Helical
Transmembrane141-159Helical
Transmembrane179-201Helical
Transmembrane230-251Helical
Transmembrane289-309Helical
Transmembrane321-341Helical
Transmembrane348-370Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-210Cytochrome b/b6 N-terminal region profile
Domain211-380Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    380
  • Mass (Da)
    42,469
  • Last updated
    2020-08-12 v1
  • Checksum
    AB58B3C1A0CDF4F2
MTGPIRKSHPLFRIVNGSLVDLPSPSNLSIWWNFGSLLGLCLIIQLITGIFLAMHYTADISLAFSSVSHICRDVNYGWLLRNVHANSASFFFICLYCHIGRGIYYGSYVNQETWNIGVILFLITMITAFVGYVLPWGQMSFWAATVITNLLSAIPYIGTDLVQWVWGGFSVDNATLTRFFTFHFLFPFIIAALSVIHLLFLHQTGSNNPTGLDSNFDKAPFHTYFSSKDLVGFLVLLTGILSLALLAPTALNDPENFIPANPLVTPVHIQPEWYFLFAYAILRSIPNKLGGVIALVAAVLVWFLVPILHTSSNQASTFRPISQIAFWSLIATFIILTWIGSQPVEEPYIIIGQIASVLYFSIFLFMFPGISVLENNLLLR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MN542416
EMBL· GenBank· DDBJ
QIT06514.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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