A0A6G7KXV4 · A0A6G7KXV4_9ASPA
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- GeneaccD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1014 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- N6-carboxybiotinyl-L-lysyl-[protein] + acetyl-CoA = N6-biotinyl-L-lysyl-[protein] + malonyl-CoA
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Cellular Component | chloroplast stroma | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Encoded on
- Chloroplast
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Asparagales > Orchidaceae > Vanilloideae > Vanilleae > Vanilla
Accessions
- Primary accessionA0A6G7KXV4
Subcellular Location
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and two subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 19-73 | Disordered | ||||
Sequence: ETMSKENMNNENMNNENMNKENMNKENMNKENMNKETKELSGKTGKTGKKLSGRK | ||||||
Compositional bias | 24-40 | Polar residues | ||||
Sequence: ENMNNENMNNENMNKEN | ||||||
Compositional bias | 41-63 | Basic and acidic residues | ||||
Sequence: MNKENMNKENMNKETKELSGKTG | ||||||
Compositional bias | 115-286 | Basic and acidic residues | ||||
Sequence: LSDRSDKSDRSDKSDRSDKSDRSDKSDRSDKSDQSDKSDRSDKSDQSDKKLSNKKLSDKSGRKVWYRSDQSDKFDQSDKSDQSDKFDQSDKSDLSDKFDQSDKSDRSDKSDRSDKRIWYKSDQSDKSDRSDKYKYKRKRSADSDKYKRKRSEEPDKYKNKRKRSANLWDDRN | ||||||
Region | 115-517 | Disordered | ||||
Sequence: LSDRSDKSDRSDKSDRSDKSDRSDKSDRSDKSDQSDKSDRSDKSDQSDKKLSNKKLSDKSGRKVWYRSDQSDKFDQSDKSDQSDKFDQSDKSDLSDKFDQSDKSDRSDKSDRSDKRIWYKSDQSDKSDRSDKYKYKRKRSADSDKYKRKRSEEPDKYKNKRKRSANLWDDRNENDLWDDEDTINLWGDKEEGDLWGDDDFAEWDSSDQSDESDQSDKSDLSKSNDSDQSIDSDLSKSNESDLSKSDKSDQSIDFDQSDKSDISNDSDQSESDKSDLSIDSDLLKSDESDQSKLDDSDLLKSDDSDISNDSDQSRSDESDQSKDSDQSDKSDLSKDSDQSKSDESDQSKLDDSDLLKSDDSDISNDSDQSKSDESDQSKDSDQSNKSDRSDKSDRSDKSDRITT | ||||||
Compositional bias | 287-323 | Acidic residues | ||||
Sequence: ENDLWDDEDTINLWGDKEEGDLWGDDDFAEWDSSDQS | ||||||
Compositional bias | 324-340 | Basic and acidic residues | ||||
Sequence: DESDQSDKSDLSKSNDS | ||||||
Compositional bias | 346-517 | Basic and acidic residues | ||||
Sequence: SDLSKSNESDLSKSDKSDQSIDFDQSDKSDISNDSDQSESDKSDLSIDSDLLKSDESDQSKLDDSDLLKSDDSDISNDSDQSRSDESDQSKDSDQSDKSDLSKDSDQSKSDESDQSKLDDSDLLKSDDSDISNDSDQSKSDESDQSKDSDQSNKSDRSDKSDRSDKSDRITT | ||||||
Compositional bias | 627-705 | Basic and acidic residues | ||||
Sequence: DQSELDESDQSKDSDQSDKSDLSKDSDLSKDSDQSESDDSDLSKSNDSDQSIDFDQSKDSDQSESDKSDQAKSDDFAEW | ||||||
Region | 627-739 | Disordered | ||||
Sequence: DQSELDESDQSKDSDQSDKSDLSKDSDLSKDSDQSESDDSDLSKSNDSDQSIDFDQSKDSDQSESDKSDQAKSDDFAEWDEFGQSMDSDQSESDEFDQSNDSDSSNKSDSSNR | ||||||
Compositional bias | 706-725 | Acidic residues | ||||
Sequence: DEFGQSMDSDQSESDEFDQS | ||||||
Domain | 748-1014 | CoA carboxyltransferase N-terminal | ||||
Sequence: FWVLCENCCITNHKRFLKARMNICEHCGFHLKMSSSDRIQFLLDPGTWEPIYEDLVAIDIDPIEFNSEDDPYIDRIHICQRKTNLTEAVQTGIGKLDSIPIAIGVMEFEFIGGSMGSVVGEKITRLIEYATNRSLPVIIVCASGGARMQEGSLSLMQMAKISSASYDYQLKKKLFYISILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEETLKKPVPEGLQETEYLFIKGSFDPIVPRKLLKGVLSELLRLHGYLPPPLN | ||||||
Zinc finger | 752-774 | C4-type | ||||
Sequence: CENCCITNHKRFLKARMNICEHC |
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,014
- Mass (Da)116,772
- Last updated2020-08-12 v1
- ChecksumAF6A9C6AD6472070
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 24-40 | Polar residues | ||||
Sequence: ENMNNENMNNENMNKEN | ||||||
Compositional bias | 41-63 | Basic and acidic residues | ||||
Sequence: MNKENMNKENMNKETKELSGKTG | ||||||
Compositional bias | 115-286 | Basic and acidic residues | ||||
Sequence: LSDRSDKSDRSDKSDRSDKSDRSDKSDRSDKSDQSDKSDRSDKSDQSDKKLSNKKLSDKSGRKVWYRSDQSDKFDQSDKSDQSDKFDQSDKSDLSDKFDQSDKSDRSDKSDRSDKRIWYKSDQSDKSDRSDKYKYKRKRSADSDKYKRKRSEEPDKYKNKRKRSANLWDDRN | ||||||
Compositional bias | 287-323 | Acidic residues | ||||
Sequence: ENDLWDDEDTINLWGDKEEGDLWGDDDFAEWDSSDQS | ||||||
Compositional bias | 324-340 | Basic and acidic residues | ||||
Sequence: DESDQSDKSDLSKSNDS | ||||||
Compositional bias | 346-517 | Basic and acidic residues | ||||
Sequence: SDLSKSNESDLSKSDKSDQSIDFDQSDKSDISNDSDQSESDKSDLSIDSDLLKSDESDQSKLDDSDLLKSDDSDISNDSDQSRSDESDQSKDSDQSDKSDLSKDSDQSKSDESDQSKLDDSDLLKSDDSDISNDSDQSKSDESDQSKDSDQSNKSDRSDKSDRSDKSDRITT | ||||||
Compositional bias | 627-705 | Basic and acidic residues | ||||
Sequence: DQSELDESDQSKDSDQSDKSDLSKDSDLSKDSDQSESDDSDLSKSNDSDQSIDFDQSKDSDQSESDKSDQAKSDDFAEW | ||||||
Compositional bias | 706-725 | Acidic residues | ||||
Sequence: DEFGQSMDSDQSESDEFDQS |