A0A6G6W845 · A0A6G6W845_9ACTN

  • Protein
    tRNA dimethylallyltransferase
  • Gene
    miaA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i6A).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, site.

131220406080100120140160180200220240260280300
Type
IDPosition(s)Description
Binding site9-16ATP (UniProtKB | ChEBI)
Binding site11-16substrate
Site100Interaction with substrate tRNA
Site121Interaction with substrate tRNA

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctiontRNA dimethylallyltransferase activity
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA dimethylallyltransferase
  • EC number
  • Alternative names
    • Dimethylallyl diphosphate:tRNA dimethylallyltransferase
      (DMAPP:tRNA dimethylallyltransferase
      ; DMATase
      )
    • Isopentenyl-diphosphate:tRNA isopentenyltransferase
      (IPP transferase
      ; IPPT
      ; IPTase
      )

Gene names

    • Name
      miaA
    • ORF names
      G5V58_00840

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • R-3366
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Propionibacteriales > Nocardioidaceae > Nocardioides

Accessions

  • Primary accession
    A0A6G6W845

Proteomes

Interaction

Subunit

Monomer.

Family & Domains

Sequence similarities

Belongs to the IPP transferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    312
  • Mass (Da)
    34,807
  • Last updated
    2020-08-12 v1
  • Checksum
    94C5759D6FFF69A0
MVPIVAVVGATASGKTTLSLDLAERLRGEVVNTDAMQVYRGMDVGTAKLPAHERRGIPHHLLDTLTVTEPATVAEFQRWAREVIDRLRAREVTPVLVGGSALYTRSVLDRFEFPGTDQEVRARWEAELAARGPHALHALLAERDPEAAAGILPENGRRTVRALEVIELTGERFSASLPVLEYADPATVQIGVDIDRETLDRRIAERVDAMFASGFVDEVRHLLDHGLEQGRTASRAIGYREVIALLRGELDETEARERTARATRRFARRQDSWFRKDPRIVWVRYDDPDRVERAVEAVGKIGRVEPGATTPD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP049257
EMBL· GenBank· DDBJ
QIG41508.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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