A0A6G6IZA0 · A0A6G6IZA0_PSENT

  • Protein
    NADH-quinone oxidoreductase subunit I
  • Gene
    nuoI
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 2 [4Fe-4S] clusters per subunit.

Features

Showing features for binding site.

118220406080100120140160180
TypeIDPosition(s)Description
Binding site62[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site65[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site68[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site72[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site101[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site104[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site107[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site111[4Fe-4S] cluster 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane respiratory chain complex I
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding
Biological Processaerobic respiration

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit I
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit I
    • NDH-1 subunit I

Gene names

    • Name
      nuoI
    • ORF names
      G5B91_18370

Organism names

  • Taxonomic identifier
  • Strain
    • HBP1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A6G6IZA0

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain52-824Fe-4S ferredoxin-type
Domain92-1214Fe-4S ferredoxin-type

Sequence similarities

Belongs to the complex I 23 kDa subunit family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    182
  • Mass (Da)
    20,645
  • Last updated
    2021-02-10 v1
  • Checksum
    7A300018F3285ECE
MIKYIFEVVHGTYTQLRSLVMIFGHAFRKRDTLQYPEEAVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETDDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEFKRQDLVYEKEDLLISGPGKNPDYNFYRVAGMAIAGKPKGAAQNEAEPINVKSLLP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP049140
EMBL· GenBank· DDBJ
QIE88130.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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