A0A6G6IQF6 · A0A6G6IQF6_PSENT
- ProteinUbiquinone/menaquinone biosynthesis C-methyltransferase UbiE
- GeneubiE
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids260 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
Catalytic activity
- a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H+ + S-adenosyl-L-homocysteine
a 2-demethylmenaquinol RHEA-COMP:9563 + CHEBI:59789 = a menaquinol RHEA-COMP:9539 + CHEBI:15378 + CHEBI:57856
Pathway
Cofactor biosynthesis; ubiquinone biosynthesis.
Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity | |
Molecular Function | demethylmenaquinone methyltransferase activity | |
Molecular Function | S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity | |
Molecular Function | S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity | |
Molecular Function | S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity | |
Biological Process | aerobic respiration | |
Biological Process | menaquinone biosynthetic process | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUbiquinone/menaquinone biosynthesis C-methyltransferase UbiE
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0A6G6IQF6
Proteomes
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-20 | Disordered | ||||
Sequence: MSEPRKPQAGQDSADPTTHF |
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length260
- Mass (Da)28,610
- Last updated2021-02-10 v1
- Checksum98952FA6BBBAE678
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP049140 EMBL· GenBank· DDBJ | QIE85212.1 EMBL· GenBank· DDBJ | Genomic DNA |