A0A6G6BRF2 · A0A6G6BRF2_9FLAO

Function

Catalytic activity

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.

Features

Showing features for active site.

132750100150200250300
TypeIDPosition(s)Description
Active site126Acyl-thioester intermediate
Active site234Proton acceptor

GO annotations

AspectTerm
Molecular Functionaspartate-semialdehyde dehydrogenase activity
Molecular FunctionNAD binding
Molecular FunctionNADP binding
Molecular Functionprotein dimerization activity
Biological Processdiaminopimelate biosynthetic process
Biological Processisoleucine biosynthetic process
Biological Processlysine biosynthetic process via diaminopimelate
Biological Processmethionine biosynthetic process
Biological Processthreonine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aspartate-semialdehyde dehydrogenase
  • EC number

Organism names

Accessions

  • Primary accession
    A0A6G6BRF2

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-117Semialdehyde dehydrogenase NAD-binding

Sequence similarities

Belongs to the aspartate-semialdehyde dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    327
  • Mass (Da)
    37,100
  • Last updated
    2020-08-12 v1
  • MD5 Checksum
    B9D7AD32A3CEC243901E6A7939770BBF
MKLGIVGITGMVGRVMIDLLEKRNFPLKELYLSASEKSIGKKFFFKKKIYKVISIYDLFLKKPDIVLFSAGSNISKEWAPKFSNIGSTVIDNSSAWRMDPCKKLIIPEINASCLCKQDKIIANPNCSTIQLVMVLFPLHIKYEIKRIIVSTYQSVTGTGKKAVNQLHKEKNGDFSCKIYPYPIYQNVLPHCDQFTDKGYTIEEMKLINETKKIINNYNIAITATAARVPVIGGHSESVNITFKKKPTIDDIYEILLKTKGIMVQDCPKKNIYPMPLYAHGKDEVFVGRIREDFSFQNSINIWIVADNIRKGAATNAIQIAEYLIKKN

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue327

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MN040539
EMBL· GenBank· DDBJ
QID54519.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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