A0A6G4JHS1 · A0A6G4JHS1_STAAU
- ProteinIron-regulated surface determinant protein B
- GeneisdB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids644 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | heme transmembrane transporter activity | |
Molecular Function | metal ion binding |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameIron-regulated surface determinant protein B
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus
Accessions
- Primary accessionA0A6G4JHS1
Subcellular Location
UniProt Annotation
GO Annotation
Secreted, cell wall ; Peptidoglycan-anchor
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 620-638 | Helical | ||||
Sequence: MTLPLMALLALSSIVAFVL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-40 | |||||
Sequence: MNKQQKEFKSFYSIRKSSLGVASAAISTLLLLMSNGEAQA | ||||||
Chain | PRO_5026173691 | 41-644 | Iron-regulated surface determinant protein B | |||
Sequence: AEETGGTNTEAQPKTEAVASPSTTTEKAPEAKPVANAVSVSNKEVEAPTSETKEAKEVKEVKAPKETKEVKPATKADNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKKDGTQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGNKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAEKLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEETKKALDEQVKSAITEFQNVQPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEAFTKANADKSNKKEQQDNSAKKETTPATPSKPTTPPVEKESQKQDSQKDDNKQSPSVEKENDASSESGKDKTPATKPAKAEVESSSTTPTKVVSTTQNVAKPTTASSETTIDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSENNKNTQENKAKSLPQTGEESNKDMTLPLMALLALSSIVAFVLPRKRKN |
Keywords
- PTM
Interaction
Subunit
Interacts with host HBA; this interaction allows heme extraction as iron source. Interacts with IsdA.
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 38-69 | Polar residues | ||||
Sequence: AQAAEETGGTNTEAQPKTEAVASPSTTTEKAP | ||||||
Region | 38-111 | Disordered | ||||
Sequence: AQAAEETGGTNTEAQPKTEAVASPSTTTEKAPEAKPVANAVSVSNKEVEAPTSETKEAKEVKEVKAPKETKEVK | ||||||
Compositional bias | 87-111 | Basic and acidic residues | ||||
Sequence: APTSETKEAKEVKEVKAPKETKEVK | ||||||
Domain | 143-268 | NEAT | ||||
Sequence: SAPNSRPIDFEMKKKDGTQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGNKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKT | ||||||
Domain | 340-457 | NEAT | ||||
Sequence: KMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEAFTKAN | ||||||
Compositional bias | 457-471 | Basic and acidic residues | ||||
Sequence: NADKSNKKEQQDNSA | ||||||
Region | 457-618 | Disordered | ||||
Sequence: NADKSNKKEQQDNSAKKETTPATPSKPTTPPVEKESQKQDSQKDDNKQSPSVEKENDASSESGKDKTPATKPAKAEVESSSTTPTKVVSTTQNVAKPTTASSETTIDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSENNKNTQENKAKSLPQTGEESNK | ||||||
Compositional bias | 472-491 | Polar residues | ||||
Sequence: KKETTPATPSKPTTPPVEKE | ||||||
Compositional bias | 492-528 | Basic and acidic residues | ||||
Sequence: SQKQDSQKDDNKQSPSVEKENDASSESGKDKTPATKP | ||||||
Compositional bias | 530-618 | Polar residues | ||||
Sequence: KAEVESSSTTPTKVVSTTQNVAKPTTASSETTIDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSENNKNTQENKAKSLPQTGEESNK | ||||||
Domain | 609-644 | Gram-positive cocci surface proteins LPxTG | ||||
Sequence: LPQTGEESNKDMTLPLMALLALSSIVAFVLPRKRKN |
Sequence similarities
Belongs to the IsdB family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length644
- Mass (Da)72,079
- Last updated2020-08-12 v1
- Checksum054C906BA6EFEF8E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 38-69 | Polar residues | ||||
Sequence: AQAAEETGGTNTEAQPKTEAVASPSTTTEKAP | ||||||
Compositional bias | 87-111 | Basic and acidic residues | ||||
Sequence: APTSETKEAKEVKEVKAPKETKEVK | ||||||
Compositional bias | 457-471 | Basic and acidic residues | ||||
Sequence: NADKSNKKEQQDNSA | ||||||
Compositional bias | 472-491 | Polar residues | ||||
Sequence: KKETTPATPSKPTTPPVEKE | ||||||
Compositional bias | 492-528 | Basic and acidic residues | ||||
Sequence: SQKQDSQKDDNKQSPSVEKENDASSESGKDKTPATKP | ||||||
Compositional bias | 530-618 | Polar residues | ||||
Sequence: KAEVESSSTTPTKVVSTTQNVAKPTTASSETTIDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSENNKNTQENKAKSLPQTGEESNK |