A0A6G1ZCW8 · A0A6G1ZCW8_9BACT

Function

function

Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site73-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site183-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Active site43Proton acceptor
Binding site451-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site501-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Active site70Proton acceptor
Binding site1001-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Site151Transition state stabilizer
Active site190Proton donor
Binding site1913-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site213-2143-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpyridoxine 5'-phosphate synthase activity
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxine 5'-phosphate synthase
  • EC number
  • Short names
    PNP synthase

Gene names

    • Name
      pdxJ
    • ORF names
      GKE01_09600

Organism names

  • Taxonomic identifier
  • Strain
    • BIOML-A4
  • Taxonomic lineage
    Bacteria > Bacteroidota > Bacteroidia > Bacteroidales > Tannerellaceae > Parabacteroides

Accessions

  • Primary accession
    A0A6G1ZCW8

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer; tetramer of dimers.

Family & Domains

Sequence similarities

Belongs to the PNP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    239
  • Mass (Da)
    26,302
  • Last updated
    2020-08-12 v1
  • Checksum
    5BCBFCC69D44C297
MTNLSVNINKVATIRNARGGNMPDILKVAQDCENFGAQGITVHPRPDERHIKYSDVYGLKPLIRTEFNIEGYPCNNFIDLVLKVKPTQVTLVPDAPDAITSNAGWDVKTHFDQLSELVDTFTAQGIRTSIFVGTDLANIELAAKTGTDRIELYTEPYATNYPANKEEAVAPFVAAAQLAKNLGMGVNAGHDLSLENLAWFSQNIPWLEEVSIGHALICDALYHGLQETISLYKACLQQK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WKLP01000012
EMBL· GenBank· DDBJ
MRY11720.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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