A0A6G0V0D1 · A0A6G0V0D1_9BILA
- Proteinaldehyde dehydrogenase (NAD(+))
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1466 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Features
Showing features for active site, binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 268 | ||||
Binding site | 1029 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 1034 | L-glutamate (UniProtKB | ChEBI) | |||
Site | 1178 | Crucial to convey clamshell closure to channel opening | |||
Binding site | 1199 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 1200 | L-glutamate (UniProtKB | ChEBI) | |||
Site | 1205 | Interaction with the cone snail toxin Con-ikot-ikot | |||
Binding site | 1250 | L-glutamate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | postsynaptic membrane | |
Molecular Function | aldehyde dehydrogenase (NAD+) activity | |
Molecular Function | ligand-gated monoatomic ion channel activity | |
Molecular Function | signaling receptor activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namealdehyde dehydrogenase (NAD(+))
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Tylenchina > Panagrolaimomorpha > Panagrolaimoidea > Panagrolaimidae > Halicephalobus
Accessions
- Primary accessionA0A6G0V0D1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 1074-1092 | Helical | |||
Transmembrane | 1149-1171 | Helical | |||
Transmembrane | 1337-1359 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 563↔834 | ||||
Disulfide bond | 1263↔1318 | ||||
Keywords
- PTM
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 938-1314 | Ionotropic glutamate receptor C-terminal | |||
Domain | 948-1018 | Ionotropic glutamate receptor L-glutamate and glycine-binding | |||
Compositional bias | 1417-1435 | Polar residues | |||
Region | 1417-1466 | Disordered | |||
Compositional bias | 1444-1466 | Polar residues | |||
Sequence similarities
Belongs to the aldehyde dehydrogenase family.
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,466
- Mass (Da)162,769
- Last updated2020-08-12 v1
- Checksum8E6B046E9C2B4827
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1417-1435 | Polar residues | |||
Compositional bias | 1444-1466 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VOSG01000034 EMBL· GenBank· DDBJ | KAE9554861.1 EMBL· GenBank· DDBJ | Genomic DNA |