A0A6G0UF73 · A0A6G0UF73_9BILA
- ProteinAcid ceramidase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids386 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- an N-acylsphing-4-enine + H2O = a fatty acid + sphing-4-enine
Pathway
Lipid metabolism; sphingolipid metabolism.
Sphingolipid metabolism.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 146 | Nucleophile | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Cellular Component | lysosome | |
Molecular Function | fatty acid amide hydrolase activity | |
Molecular Function | N-acylsphingosine amidohydrolase activity | |
Biological Process | fatty acid metabolic process | |
Biological Process | sphingolipid metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcid ceramidase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Tylenchina > Panagrolaimomorpha > Panagrolaimoidea > Panagrolaimidae > Halicephalobus
Accessions
- Primary accessionA0A6G0UF73
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-20 | |||||
Sequence: MKSLLYFLCFFVFASSPILA | ||||||
Chain | PRO_5026134113 | 21-386 | Acid ceramidase | |||
Sequence: QDDPADPFGIYGAVCLAGKEGLYNPANAFGVPWFNIDLDESPLTRWNTVGQIYGKKMESTVQTVKTMAGIILDGLLWDVLIQLMNTAYPQIPQPYRDELKGMADASGVSIEELTLLNLFYEISKGCTSIVAEDSNGIIYHARNQDFGTFFIWEGPENHQWAQTEGLRDLLINVNFIKGGKVLFKGVTFAGHLGILTGLKPNAFTLSTNARAGSTLNNLINFFINGPMGKQFLIYADREVLESANSYSEAMDYLQNVPLFAYGYFIVGGASSGEGAIITRNPNGTDHVQTLDRTKPGGWYVLQTNYDWDKEVLYLDDRRGPGHTCMNKLTQNKVGLAGLFQVLSSKPNLNKATVYTSVMQVNTPVLE |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 51-104 | Acid ceramidase N-terminal | ||||
Sequence: VPWFNIDLDESPLTRWNTVGQIYGKKMESTVQTVKTMAGIILDGLLWDVLIQLM | ||||||
Domain | 146-325 | Choloylglycine hydrolase/NAAA C-terminal | ||||
Sequence: CTSIVAEDSNGIIYHARNQDFGTFFIWEGPENHQWAQTEGLRDLLINVNFIKGGKVLFKGVTFAGHLGILTGLKPNAFTLSTNARAGSTLNNLINFFINGPMGKQFLIYADREVLESANSYSEAMDYLQNVPLFAYGYFIVGGASSGEGAIITRNPNGTDHVQTLDRTKPGGWYVLQTNY |
Sequence similarities
Belongs to the acid ceramidase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length386
- Mass (Da)42,673
- Last updated2020-08-12 v1
- ChecksumA173AF648CE10289
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 386 | |||||
Sequence: E |
Keywords
- Technical term