A0A6G0UDY8 · A0A6G0UDY8_9BILA
- ProteinAcyl-CoA dehydrogenase family member 11
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids920 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA. Probably participates in beta-oxydation and energy production but could also play a role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain.
Catalytic activity
- hexacosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H+ = (2E)-hexacosenoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- tetracosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H+ = (2E)-tetracosenoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- tricosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H+ = (2E)-tricosenoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- a 2,3-saturated acyl-CoA + oxidized [electron-transfer flavoprotein] + H+ = a (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- docosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H+ = (2E)-docosenoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
- eicosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H+ = (2E)-eicosenoyl-CoA + reduced [electron-transfer flavoprotein]This reaction proceeds in the forward direction.
Cofactor
Pathway
Lipid metabolism; fatty acid beta-oxidation.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial membrane | |
Molecular Function | acyl-CoA dehydrogenase activity | |
Molecular Function | flavin adenine dinucleotide binding | |
Biological Process | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Recommended nameAcyl-CoA dehydrogenase family member 11
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Tylenchina > Panagrolaimomorpha > Panagrolaimoidea > Panagrolaimidae > Halicephalobus
Accessions
- Primary accessionA0A6G0UDY8
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 227-453 | Aminoglycoside phosphotransferase | |||
Domain | 574-697 | Acyl-CoA dehydrogenase/oxidase N-terminal | |||
Domain | 701-804 | Acyl-CoA oxidase/dehydrogenase middle | |||
Domain | 830-919 | Acyl-CoA dehydrogenase/oxidase C-terminal | |||
Sequence similarities
Belongs to the acyl-CoA dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length920
- Mass (Da)104,128
- Last updated2020-08-12 v1
- MD5 ChecksumA481B5AFFE55717C164D838CAB72FF47
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VOSG01001045 EMBL· GenBank· DDBJ | KAE9547284.1 EMBL· GenBank· DDBJ | Genomic DNA |