A0A6F8UX90 · A0A6F8UX90_9HYPH

  • Protein
    Guanine deaminase
  • Gene
    guaD1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionguanine deaminase activity
Molecular Functionzinc ion binding
Biological Processguanine catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Guanine deaminase
  • EC number
  • Short names
    Guanase
  • Alternative names
    • Guanine aminohydrolase

Gene names

    • Name
      guaD1
    • ORF names
      OCUBac02_35120

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ANAM02
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Boseaceae > Bosea

Accessions

  • Primary accession
    A0A6F8UX90

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain77-437Amidohydrolase-related

Sequence similarities

Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    447
  • Mass (Da)
    48,783
  • Last updated
    2020-08-12 v1
  • Checksum
    9A085F86A17DAA89
MPEPPIVTAPAALRALRGRLLWFVDDPVVAGEAAHRFIQDGLLIIENGLVRAAGEAQDLLRTLPADAEIVDHRPHLIMPGFIDAHIHMPQTQVLASYGAQLMEWLNKYTFVEEQKLAQQGHAEKLSRFFLDELLANGTTTAAVYASVHPQSAEAFFSESQRRNIRMIAGKVMMDRNAPEALTDTAESGYRDSKALIARWHGKGRQLYAITPRFAITSTPEQMAAAGKLAAEHPDCHVQTHIDENRAEIAFARELYPEAADYADIYRRYGLLGAKSLMGHCIHMTHNEWQAFAEAGAVAVFCPTSNLFLGSGLFDWAHARQRGVKVAVATDIGGGTSYSMLRTMAEAYKVLQLQGQSLSALEALHAITRGNAVALGLDHWIGSFEPGREADVVVLDTSATRAMAHRLETVRDLAEELFVLVTLGDDRNVVATYVMGELAAGASFSGGA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP022848
EMBL· GenBank· DDBJ
BCB20618.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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