A0A6F8U141 · A0A6F8U141_9GAMM

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Can also use Mn2+ ion.

Features

Showing features for binding site, active site.

153250100150200250300350400450500
TypeIDPosition(s)Description
Binding site101-103substrate
Binding site184Mg2+ (UniProtKB | ChEBI)
Active site222Proton acceptor
Binding site223-224substrate
Binding site260substrate
Binding site381-385substrate
Binding site452substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionisocitrate lyase activity
Molecular Functionmetal ion binding
Biological Processcarboxylic acid metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Isocitrate lyase
  • Alternative names
    • Isocitrase
    • Isocitratase

Gene names

    • ORF names
      HHSLTHF2_10620

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Slthf2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Oceanospirillales > Halomonadaceae > Halomonas

Accessions

  • Primary accession
    A0A6F8U141

Proteomes

Family & Domains

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    532
  • Mass (Da)
    59,103
  • Last updated
    2020-08-12 v1
  • Checksum
    4CE56DA38A1ED81D
MSGLLDDIKAMAQLREAQGGKWEAIKPEYAARMRAQNRFHTGLDIARYTAKIMRDDMAAYDADTSKYTQSLGCWHGFIGQQKLISIKKHFGTTKRSYLYLSGWMVAALRSEFGPLPDQSMHEKTSVADLIEELYTFLKQADAWELNHLFRALDDAKEAGDSAKEQELISKIDNYETHIVPIIADIDAGFGNAEATYLLAKKFIQAGACCIQLENQVSDEKQCGHQDGKVTVPHEDFLAKINAVRYAFLELGIEDGVIVARTDSLGAGLTQKIAVTNEPGDLGDQYNSFLDGDVIENASDINNGDVVIKQNGQLVKPKRLASGLYQFKPGTGEDRVVLDCITSLQNGADLLWIETEKPHVGQIASMVNRIRAVVPDAKLVYNNSPSFNWTLNFRQQVFDAWEKEGKDVSAYQRDKLMGVEYDNTELGQLADEWTRNFQRDGAREAGIFHHLITLPTYHTAALSTDNLAKGYFGDEGMLAYVAGVQRQEIRQGIATVKHQDMAGSNIGDDHKEFFHGDAALKAGGKDNTMNQFG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP022843
EMBL· GenBank· DDBJ
BCB07172.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp