A0A6F8TUH6 · A0A6F8TUH6_9BACI

  • Protein
    3-phosphoshikimate 1-carboxyvinyltransferase
  • Gene
    aroA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site243-phosphoshikimate (UniProtKB | ChEBI)
Binding site24phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site253-phosphoshikimate (UniProtKB | ChEBI)
Binding site293-phosphoshikimate (UniProtKB | ChEBI)
Binding site96phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site124phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site1693-phosphoshikimate (UniProtKB | ChEBI)
Binding site1713-phosphoshikimate (UniProtKB | ChEBI)
Binding site171phosphoenolpyruvate (UniProtKB | ChEBI)
Active site316Proton acceptor
Binding site3163-phosphoshikimate (UniProtKB | ChEBI)
Binding site3433-phosphoshikimate (UniProtKB | ChEBI)
Binding site347phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site389phosphoenolpyruvate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-phosphoshikimate 1-carboxyvinyltransferase activity
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-phosphoshikimate 1-carboxyvinyltransferase
  • EC number
  • Alternative names
    • 5-enolpyruvylshikimate-3-phosphate synthase
      (EPSP synthase
      ; EPSPS
      )

Gene names

    • Name
      aroA
    • ORF names
      KH172YL63_26590

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KH172YL63
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus

Accessions

  • Primary accession
    A0A6F8TUH6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-423Enolpyruvate transferase

Sequence similarities

Belongs to the EPSP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    432
  • Mass (Da)
    46,447
  • Last updated
    2020-08-12 v1
  • Checksum
    ED1D75B3B883E5E6
MEETKRLINPKRGLKGKLEVPGDKSISHRSIMFGSIAEGKTVIHNFLMGEDCLSTISCFRKLGVDIDVSEDEVVVHGKGWDHLKEPKDILDVGNSGTTTRLIMGILAGRPFHSVLIGDDSIAKRPMNRVTIPLRQFGTNIDGRSEGNYTPLSVRGGNLKAIRYSLPVASAQVKSAILLAGLQAEGTTEIVEPEKTRNHTEKMIVEFGGSVEREGDTIKVKGGQVFKGTDIYVPGDISSAAFFMVAAAIVPGSSVRLKNVGLNETRIGIIEVMKKMGAAIEVIEHTKSGEPIGDIVVQSSELTGIEIGGELIPSLIDEIPVIALLASQANGKTVIKDAEELKVKETNRIDAVVKELGKLGADIEGTDDGMIIHGKTELHGGEVHSWGDHRIGMTLAVASLLTDSDVYLDGSEAVKISYPQFFDHIDLLLGNES

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP022842
EMBL· GenBank· DDBJ
BCB04526.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp