A0A6F8TUF4 · A0A6F8TUF4_9BACI
- ProteinPyrimidine-nucleoside phosphorylase
- Genepdp
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids434 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
Catalytic activity
- 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 1,4-alpha-oligoglucan phosphorylase activity | |
Molecular Function | deoxyuridine phosphorylase activity | |
Molecular Function | metal ion binding | |
Molecular Function | thymidine phosphorylase activity | |
Biological Process | pyrimidine nucleobase metabolic process | |
Biological Process | pyrimidine nucleoside metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyrimidine-nucleoside phosphorylase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus
Accessions
- Primary accessionA0A6F8TUF4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 345-418 | Pyrimidine nucleoside phosphorylase C-terminal | ||||
Sequence: YVSEIVADAVGTAAMWLGAGRATKDSVIDLAVGLELRKKIGDTVKAGDSLVTIYSNDENIDQVKEKLYESIKVT |
Sequence similarities
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length434
- Mass (Da)46,368
- Last updated2020-08-12 v1
- Checksum6BFE49C9A8E26FC6