A0A6F8TNB1 · A0A6F8TNB1_9BACI

  • Protein
    Kynurenine formamidase
  • Gene
    kynB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 zinc ions per subunit.

Pathway

Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site17substrate
Binding site47Zn2+ 1 (UniProtKB | ChEBI)
Binding site51Zn2+ 1 (UniProtKB | ChEBI)
Binding site53Zn2+ 2 (UniProtKB | ChEBI)
Binding site53Zn2+ 1 (UniProtKB | ChEBI)
Active site57Proton donor/acceptor
Binding site158Zn2+ 2 (UniProtKB | ChEBI)
Binding site170Zn2+ 2 (UniProtKB | ChEBI)
Binding site170Zn2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionarylformamidase activity
Molecular Functionformamidase activity
Molecular Functionzinc ion binding
Biological Processtryptophan catabolic process to kynurenine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Kynurenine formamidase
  • EC number
  • Short names
    KFA
    ; KFase
  • Alternative names
    • Arylformamidase
    • N-formylkynurenine formamidase
      (FKF
      )

Gene names

    • Name
      kynB
    • ORF names
      KH172YL63_04890

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KH172YL63
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus

Accessions

  • Primary accession
    A0A6F8TNB1

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the Cyclase 1 superfamily. KynB family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    207
  • Mass (Da)
    22,661
  • Last updated
    2020-08-12 v1
  • Checksum
    C98C4EDAB5DC6EE5
MKIIDISRPLHNDTPVWPGDTPFSFSLNWTKEETGSVNVGQVTMSSHTGTHVDAPFHFDQDGNRILDLPLERFMGQAVVVSVEGAEEITPEQLKDIDFSGVTKILFKTNAWKNPDQFPEEIPPVSEELGPFLKQNGIDLIGVDLPSVDQLDSKELNAHHSLHANGIGILEGIVLTDVNPGRYELVALPLPLQDGDGSPVRAVLVERG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP022842
EMBL· GenBank· DDBJ
BCB02356.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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