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A0A6D2XIL2 · A0A6D2XIL2_PANTR

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for binding site, active site.

1138102030405060708090100110120130
Type
IDPosition(s)Description
Binding site47Ca2+ (UniProtKB | ChEBI)
Binding site49Ca2+ (UniProtKB | ChEBI)
Binding site51Ca2+ (UniProtKB | ChEBI)
Active site67
Binding site68Ca2+ (UniProtKB | ChEBI)
Active site111

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functioncalcium ion binding
Molecular Functioncalcium-independent phospholipase A2 activity
Biological Processarachidonic acid secretion
Biological Processcardiolipin acyl-chain remodeling
Biological Processleukotriene biosynthetic process
Biological Processphosphatidylcholine catabolic process
Biological Processpositive regulation of ERK1 and ERK2 cascade
Biological Processpositive regulation of immune complex clearance by monocytes and macrophages
Biological Processpositive regulation of phospholipase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phospholipase A2
  • EC number

Gene names

    • ORF names
      CK820_G0039342

Organism names

  • Taxonomic identifier
  • Strain
    • Yerkes chimp pedigree #C0471
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan

Accessions

  • Primary accession
    A0A6D2XIL2

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-20
ChainPRO_502570978521-138Phospholipase A2
Disulfide bond48↔64
Disulfide bond63↔117
Disulfide bond70↔110
Disulfide bond79↔103
Disulfide bond97↔108

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain21-138Phospholipase A2

Sequence similarities

Belongs to the phospholipase A2 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    138
  • Mass (Da)
    15,718
  • Last updated
    2020-06-17 v1
  • MD5 Checksum
    556A622D378E057E531116FCCEAD651C
MKGLLPLAWFLACSVPTVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGTDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVKLCACDRKLVYCLKRNLRSYNPQYQYFPNILCS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NBAG03000373
EMBL· GenBank· DDBJ
PNI33508.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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