A0A6D2WPC6 · A0A6D2WPC6_PONAB

Function

function

ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. Oxidizes medium and long chain aldehydes into non-toxic fatty acids. Preferentially oxidizes aromatic aldehyde substrates. Comprises about 50 percent of corneal epithelial soluble proteins. May play a role in preventing corneal damage caused by ultraviolet light.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site210
Active site244

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentendoplasmic reticulum
Cellular Componentplasma membrane
Molecular Function3-chloroallyl aldehyde dehydrogenase activity
Molecular Functionalcohol dehydrogenase (NADP+) activity
Molecular Functionbenzaldehyde dehydrogenase (NAD+) activity
Biological Processcellular aldehyde metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Aldehyde dehydrogenase

Gene names

    • Name
      ALDH3A1
    • ORF names
      CR201_G0051956

Organism names

Accessions

  • Primary accession
    A0A6D2WPC6
  • Secondary accessions
    • A0A2J8RC42
    • H2NVB9

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, coiled coil.

TypeIDPosition(s)Description
Domain3-425Aldehyde dehydrogenase
Coiled coil23-50

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    453
  • Mass (Da)
    50,479
  • Last updated
    2020-06-17 v1
  • Checksum
    30B5078E6DA157DD
MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALRRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYMLCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPLLPIVCVRSLEEAIQFINQREKPLALYVFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEALKVRYPPSPAKMTWH

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2J8RC43A0A2J8RC43_PONABALDH3A1389

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NDHI03003712
EMBL· GenBank· DDBJ
PNJ06096.1
EMBL· GenBank· DDBJ
Genomic DNA
NDHI03003712
EMBL· GenBank· DDBJ
PNJ06097.1
EMBL· GenBank· DDBJ
Genomic DNA
NDHI03003712
EMBL· GenBank· DDBJ
PNJ06101.1
EMBL· GenBank· DDBJ
Genomic DNA
NDHI03003712
EMBL· GenBank· DDBJ
PNJ06103.1
EMBL· GenBank· DDBJ
Genomic DNA
NDHI03003712
EMBL· GenBank· DDBJ
PNJ06104.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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