A0A6C6ZXK3 · A0A6C6ZXK3_SALDC

Function

function

Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site.

161450100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site85cyanocob(III)alamin (UniProtKB | ChEBI)
Binding site92cyanocob(III)alamin (UniProtKB | ChEBI)
Binding site110-111cyanocob(III)alamin (UniProtKB | ChEBI)
Binding site199Ca2+ 1 (UniProtKB | ChEBI)
Binding site211Ca2+ 1 (UniProtKB | ChEBI)
Binding site213Ca2+ 1 (UniProtKB | ChEBI)
Binding site213Ca2+ 2 (UniProtKB | ChEBI)
Binding site215Ca2+ 2 (UniProtKB | ChEBI)
Binding site215Ca2+ 1 (UniProtKB | ChEBI)
Binding site249Ca2+ 2 (UniProtKB | ChEBI)
Binding site250Ca2+ 1 (UniProtKB | ChEBI)
Binding site250Ca2+ 2 (UniProtKB | ChEBI)
Binding site251cyanocob(III)alamin (UniProtKB | ChEBI)
Binding site261Ca2+ 2 (UniProtKB | ChEBI)
Binding site309cyanocob(III)alamin (UniProtKB | ChEBI)
Binding site517cyanocob(III)alamin (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcell outer membrane
Cellular Componentpore complex
Molecular FunctionABC-type vitamin B12 transporter activity
Molecular Functionmetal ion binding
Molecular Functionporin activity
Biological Processmonoatomic ion transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Vitamin B12 transporter BtuB
  • Alternative names
    • Cobalamin receptor
    • Outer membrane cobalamin translocator

Gene names

    • Name
      btuB
    • Ordered locus names
      SeD_A4536

Organism names

Accessions

  • Primary accession
    A0A6C6ZXK3

Proteomes

Subcellular Location

Cell outer membrane
; Multi-pass membrane protein

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_502573754721-614Vitamin B12 transporter BtuB

Family & Domains

Features

Showing features for motif, domain.

TypeIDPosition(s)Description
Motif26-33TonB box
Motif27-33TonB box
Domain41-146TonB-dependent receptor plug
Domain170-588TonB-dependent receptor-like beta-barrel
Motif597-614TonB C-terminal box

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    614
  • Mass (Da)
    68,468
  • Last updated
    2020-06-17 v1
  • Checksum
    ADF10BD637D04FDC
MIKKATLLTAFSVTAFSAWAQDTSPDTLVVTANRFQQPRSAVLAPVTIVTRQDIERWQSTSVNDVLRRLPGVDIAQSGGAGQNSSIFIRGTNSSHVLVLIDGVRLNLAGVSGSADLSQFPVSLVQRIEYIRGPRSAIYGSDAIGGVVNIITTRDNPGTELTAGWGSNSYQNYDISTQQQLGENTRATLIGDYEYTKGFDVVAKGGTGMQAQPDRDGFLSKTLYGALEHTFSDRWSGFVRGYGYDNRTDYDAYYSPGSPLIDTRKLYSQSWDAGLRFNGERIQSQLVSSYSHSKDYNYDPHYGRYDTSATLDEMKQYNVQWTNSVVVGHGNVGAGVDWQKQTTTPGTGYVPEGYDQRNTGVYLTGLQQLGDFTLEAAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGASYKAPNLGQLYGYYGNPNLNPEKSKQWEGAFEGLTAGVSWRISGYRNDINDMIDYDDHLQKYYNEGKARIKGIEATANFDTGPLTHTVSYDYVDARNAVTDTPLPRRSKQMAKYQLDWDVYDFDWGVTYQYLGSRYDSDYSAYPYRTVKMGGVSLWDLTVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001144
EMBL· GenBank· DDBJ
ACH75360.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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